204574-95-8

Basic information

• Product Name: Carbamic acid, (2-methylenecyclopentyl)-, 1,1-dimethylethyl ester (9CI)
• Synonyms: Carbamic acid, (2-methylenecyclopentyl)-, 1,1-dimethylethyl ester (9CI)
• CAS NO: 204574-95-8
• Molecular Formula: C11H19NO2
• Molecular Weight: 197.27406
• Product Categories: N-BOC
• Mol File: 204574-95-8.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 283.4±20.0 °C(Predicted)
• Appearance: /
• Density: 0.99±0.1 g/cm3(Predicted)
• PKA: 12.15±0.20(Predicted)
• CAS DataBase Reference: Carbamic acid, (2-methylenecyclopentyl)-, 1,1-dimethylethyl ester (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, (2-methylenecyclopentyl)-, 1,1-dimethylethyl ester (9CI)(204574-95-8)
• EPA Substance Registry System: Carbamic acid, (2-methylenecyclopentyl)-, 1,1-dimethylethyl ester (9CI)(204574-95-8)

Safety Data

• Hazardous Substances Data: 204574-95-8(Hazardous Substances Data)

Upstream product

• 821-41-0 5-Hexen-1-ol 
• 2396-80-7 methyl 5-hexenoate 
• 204574-73-2 (E/Z)-5-hexenal O-methyloxime 
• 24424-99-5 di-tert-butyl dicarbonate 
• 764-59-0 hex-5-en-1-al 
• 204574-94-7 (2-Phenylsulfanylmethyl-cyclopentyl)-carbamic acid tert-butyl ester 
• 474759-19-8 (E)-5-hexenal diphenylhydrazone 

Downstream Products

• 136315-70-3 (±)-cis-2-((tert-butoxycarbonyl)amino)cyclopentanecarboxylic acid 

Relevant articles and documents

Radical cyclization in heterocycle synthesis. Part 13: Sulfanyl radical addition-cyclization of oxime ethers and hydrazones connected with alkenes for synthesis of cyclic β-amino acids

A combination of sulfanyl radical addition-cyclization of the oxime ethers and hydrazones connected with alkenes and subsequent conversion of a phenylsulfanylmethyl group to a carboxyl group provides a novel method for the construction of the cyclic β-amino acids. Upon treatment with thiophenol in the presence of AIBN, the oxime ethers and hydrazones smoothly underwent sulfanyl radical addition-cyclization to give the 2-(phenylsulfanylmethyl)cycloalkylamine. This method was successfully applied to the practical synthesis of 2-aminocyclopentanecarboxylic acid and 4-amino-3-pyrrolidinecarboxylic acid.