474759-19-8

Basic information

• Product Name: (E)-5-hexenal diphenylhydrazone
• Synonyms: (E)-5-hexenal diphenylhydrazone
• CAS NO: 474759-19-8
• Molecular Weight: 264.37
• Mol File: 474759-19-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (E)-5-hexenal diphenylhydrazone(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-5-hexenal diphenylhydrazone(474759-19-8)
• EPA Substance Registry System: (E)-5-hexenal diphenylhydrazone(474759-19-8)

Safety Data

• Hazardous Substances Data: 474759-19-8(Hazardous Substances Data)

Upstream product

• 821-41-0 5-Hexen-1-ol 
• 2396-80-7 methyl 5-hexenoate 
• 764-59-0 hex-5-en-1-al 
• 530-47-2 N,N-diphenylhydrazine hydrochloride 

Downstream Products

• 204574-95-8 1,1-dimethylethyl [2-(methylene)cyclopentyl]carbamate 
• 136315-70-3 (±)-cis-2-((tert-butoxycarbonyl)amino)cyclopentanecarboxylic acid 

Relevant articles and documents

Radical cyclization in heterocycle synthesis. Part 13: Sulfanyl radical addition-cyclization of oxime ethers and hydrazones connected with alkenes for synthesis of cyclic β-amino acids

A combination of sulfanyl radical addition-cyclization of the oxime ethers and hydrazones connected with alkenes and subsequent conversion of a phenylsulfanylmethyl group to a carboxyl group provides a novel method for the construction of the cyclic β-amino acids. Upon treatment with thiophenol in the presence of AIBN, the oxime ethers and hydrazones smoothly underwent sulfanyl radical addition-cyclization to give the 2-(phenylsulfanylmethyl)cycloalkylamine. This method was successfully applied to the practical synthesis of 2-aminocyclopentanecarboxylic acid and 4-amino-3-pyrrolidinecarboxylic acid.