2046-19-7

Basic information

• Product Name: D-2-AMINO-5-PHENYL-PENTANOIC ACID
• Synonyms: (R)-2-AMINO-5-PHENYL-PENTANOIC ACID;H-D-NVA(5-PHENYL)-OH;D-2-AMINO-5-PHENYL-PENTANOIC ACID;D-Nva(5-phenyl)-OH;D-PEA;Benzenepentanoic acid, .alpha.-amino-
• CAS NO: 2046-19-7
• Molecular Formula: C11H15NO2
• Molecular Weight: 193.24
• Product Categories: Phenylalanine analogs and other aromatic alpha amino acids;a-amino
• Mol File: 2046-19-7.mol
• Article Data: 14

Chemical Properties

• Boiling Point: 375.2 °C at 760 mmHg
• Flash Point: 180.7 °C
• Appearance: /
• Density: 1.133 g/cm³
• Vapor Pressure: 2.69E-06mmHg at 25°C
• Refractive Index: 1.555
• Sensitive: Air Sensitive
• CAS DataBase Reference: D-2-AMINO-5-PHENYL-PENTANOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: D-2-AMINO-5-PHENYL-PENTANOIC ACID(2046-19-7)
• EPA Substance Registry System: D-2-AMINO-5-PHENYL-PENTANOIC ACID(2046-19-7)

Safety Data

• Hazardous Substances Data: 2046-19-7(Hazardous Substances Data)

Usage

General Description

D-2-Amino-5-Phenyl-Pentanoic Acid, also known as D-2-Amino-5-Phenylvaleric Acid or D-Leucine, is a chemical compound with the molecular formula C11H15NO2. It belongs to the category of amino acids, peptides, and analogues, specifically those that carry an aromatic phenyl group, or ring. D-2-AMINO-5-PHENYL-PENTANOIC ACID usually comes in crystalline or powder form and is often used in scientific research, particularly involving the roles and functions of amino acids in biological systems. However, potential applications are subject to scientific research and approvals. As with all chemicals, it should be handled with care to avoid any potential harm or health risks.

InChI:InChI=1/C11H15NO2/c12-10(11(13)14)8-4-7-9-5-2-1-3-6-9/h1-3,5-6,10H,4,7-8,12H2,(H,13,14)

Upstream product

• 84299-13-8 bromo-(3-phenyl-propyl)-malonic acid 
• 108019-30-3 DL-N-acetyl-2-amino-5-phenylpentanoic acid 
• 88768-11-0 2-oxo-5-phenylpentanoic acid 
• 121704-10-7 2-(2-Methoxy-acetylamino)-5-phenyl-pentanoic acid 
• 637-59-2 1-Bromo-3-phenylpropane 
• 81867-09-6 ethyl 2-oxo-5-phenylpentanoate 
• 852298-85-2 (4S,5R)-1-((S)-2-Azido-5-phenyl-pentanoyl)-3,4-dimethyl-5-phenyl-imidazolidin-2-one 
• 852298-77-2 (4S,5R)-1-((R)-2-Bromo-5-phenyl-pentanoyl)-3,4-dimethyl-5-phenyl-imidazolidin-2-one 
• 852298-94-3 (S)-2-Azido-5-phenyl-pentanoic acid 
• 62732-55-2 2-Acetylamino-2-(3-phenyl-propyl)-malonic acid 
• 591-50-4 iodobenzene 
• 61172-66-5 2-((tert-butoxycarbonyl)amino)pent-4-ynoic acid 
• 1068-90-2 2-acetylaminomalonic acid diethyl ester 
• 1794-48-5 1-bromo-3-phenylprop-2-yne 

Downstream Products

• 400886-12-6 (S)-2-Amino-5-phenyl-pentanoic acid allyl ester 
• 110849-10-0 2-(t-butoxycarbonylamino)-5-phenylpentanoic acid 

Relevant articles and documents

Effective synthesis of optically active 3-phenyl-3-(3-trifluoromethyl) diazirinyl bishomophenylalanine derivatives

Effective incorporation of phenyldiazirine moiety on the acyl residue of L- and D- glutamic acid by Friedel-Crafts reactions with triflic acid developed simple preparation of bishomophenylalanine (bhPhe) for aromatics, which added a

Controlling diastereoselectivity in the reactions of enantiomerically pure α-bromoacyl-imidazolidinones with nitrogen nucleophiles: Substitution reactions with retention or inversion of configuration

Diastereoselective substitution reactions of α-bromoacyl- imidazolidinones with nitrogen nucleophiles can be promoted with either retention or inversion of configuration by carrying out reactions under epimerising or non-epimerising conditions. The Royal Society of Chemistry 2005.

STEREOSELECTIVE PROCESS FOR THE SYNTHESIS OF (D)-2-AMINO-5-PHENYLPENTANOIC OR ALKYL ESTER THEREOF

The present invention provides a process for preparing a compound of formula (I); wherein R is a C1-C6 alkyl; or a salt thereof; comprising:(c) hydrolyzing (D,L)-N-acetyl-2-amino-5-phenylpentanoic acid with a suitable base in the pre