2048-34-2

Upstream product

• 122058-30-4 4-methylcinnamyl alcohol 
• 1866-39-3 4-methylcinnamic acid 
• 7560-43-2 methyl 3-(4-methylphenyl)acrylate 
• 58824-48-9 1-(4-methylphenyl)-2-propen-1-ol 
• 104-87-0 4-methyl-benzaldehyde 
• 2749-96-4 4-methylphenylallene 
• 1504-75-2 3-(4-methylphenyl)acrylaldehyde 

Downstream Products

• 56578-35-9 4-methyl-cinnamaldehyde 
• 77134-00-0 3-(4-methylphenyl)prop-2-enyl acetate 
• 54636-59-8 6-(p-Methylphenyl)-3-phenyl-5-hexen-2-on 
• 122058-30-4 4-methylcinnamyl alcohol 
• 7642-17-3 1-Methyl-4-((E)-pent-1-enyl)-benzene 
• 30779-92-1 (E)-3-(4-methylbenzylidene)-4-chromanone 
• 54636-57-6 C₂₆H₃₂O₃ 
• 1587704-75-3 (R)-1-(p-tolyl)allyl propylcarbamate 
• 1494998-77-4 N-propyl-1-(p-tolyl)prop-2-en-1-amine 

Relevant academic research and scientific papers

PdII/Novel Chiral Cinchona Alkaloid Oxazoline-Catalyzed Enantioselective Oxidative Cyclization of Aromatic Alkenyl Amides

A highly enantioselective PdII-catalyzed aza-Wacker oxidation tandem cyclization of aromatic nitrogen-containing dienes has been achieved in the presence of novel chiral cinchona alkaloid oxazoline ligands for the first time, affording chiral dihydroindole nitrogen-containing polycyclic compounds with good yields (up to 83 %), high diastereoselectivities (> 95:5 dr), and excellent enantioselectivities (up to 97 % ee).

A Convenient Palladium-Catalyzed Carbonylative Synthesis of (E)-3-Benzylidenechroman-4-ones

A convenient palladium-catalyzed carbonylation reaction for the efficient synthesis of (E)-3-benzylidenechroman-4-ones has been developed. Using TFBen as a solid CO source, a range of substituted (E)-3-benzylidenechroman-4-ones were prepared in moderate to good yields with 2-iodophenols and allyl chlorides as the substrates. Additionally, substituted quinolin-4(1H)-ones can also be obtained with 2-iodoaniline as the starting material.

Selectfluor-mediated mild oxidative halogenation and thiocyanation of 1-aryl-allenes with TMSX (X = Cl, Br, I, NCS) and NH4SCN

Presence of TMSX (X = Cl, Br, I) unleashes the oxidative character of Selectfluor and provides a mild dihalogenation method for 1-arylallenes. Preference for 2,3-addition was observed with TMSCl in MeCN irrespective of the nature of the substituent on the aryl moiety, whereas 1,2-addition was preferred in [BMIM][BF4]. With TMSBr and TMSI only products corresponding to 2,3-addition were observed. Reactions carried out with TMSBr in IL solvents gave the corresponding monobromoalkenes as a major product along with the isomeric dibromo-alkenes. Reaction with NH4SCN provided convenient access to dithiocyanate derivatives. The same products were formed via TMS-NCS/Selectfluor. Formation of common products via TMSNCS and NH 4SCN points to the formation and interplay of SCN+/ NCS+ as incipient electrophiles.