204926-79-4

Basic information

• Product Name: N-butyl-2-ethylphenylamine
• Synonyms: N-butyl-2-ethylphenylamine
• CAS NO: 204926-79-4
• Molecular Weight: 177.29
• Mol File: 204926-79-4.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: N-butyl-2-ethylphenylamine(CAS DataBase Reference)
• NIST Chemistry Reference: N-butyl-2-ethylphenylamine(204926-79-4)
• EPA Substance Registry System: N-butyl-2-ethylphenylamine(204926-79-4)

Safety Data

• Hazardous Substances Data: 204926-79-4(Hazardous Substances Data)

Upstream product

• 62-53-3 aniline 
• 71-36-3 butan-1-ol 
• 109-65-9 1-bromo-butane 
• 578-54-1 ortho-ethylaniline 
• 109-72-8 n-butyllithium 
• 35774-47-1 1-azido-2-ethylbenzene 

Relevant articles and documents

Colloidal and Nanosized Catalysts in Organic Synthesis: XX. Continuous Hydrogenation of Imines and Enamines Catalyzed by Nickel Nanoparticles

Nickel nanoparticles on the BAU-A active carbon or NaX zeolite catalyze hydrogenation of imines and enamines in a flow reactor in a gas phase or in a gas–liquid–solid catalyst system. The process occurs at atmospheric pressure of hydrogen and gives secondary or tertiary amines in a high yield.

Development of Quinoline-2,4(1H,3H)-diones as Potent and Selective Ligands of the Cannabinoid Type 2 Receptor

The cannabinoid type 2 receptors (CB2Rs) play crucial roles in inflammatory diseases. There has been considerable interest in developing potent and selective ligands for CB2R. In this study, quinoline-2,4(1H,3H)-dione analogs have been designed, synthesized, and evaluated for their potencies and binding properties toward the cannabinoid type 1 receptor (CB1R) and CB2R. C5- or C8-substituted quinoline-2,4(1H,3H)-diones demonstrate CB2R agonist activity, while the C6- or C7-substituted analogs are antagonists of CB2R. In addition, oral administration of 21 dose-dependently alleviates the clinical symptoms of experimental autoimmune encephalomyelitis in a mouse model of multiple sclerosis and protects the central nervous system from immune damage. Furthermore, the interaction modes predicted by docking simulations and the 3D-QSAR model generated with CoMFA may offer guidance for further design and modification of CB2R modulators.