204988-85-2

Upstream product

• 606-23-5 1H-indene-1,3(2H)-dione 
• 39145-31-8 2-cyano-3-(4-methoxyphenyl)thioacrylamide 
• 7357-70-2 Cyanothioacetamide 
• 7421-76-3 2-(4-methoxybenzylidene)indane-1,3-dione 

Downstream Products

• 204989-05-9 2-Cyanomethylsulfanyl-4-(4-methoxy-phenyl)-5-oxo-5H-indeno[1,2-b]pyridine-3-carbonitrile 
• 204989-03-7 2-[3-Cyano-4-(4-methoxy-phenyl)-5-oxo-5H-indeno[1,2-b]pyridin-2-ylsulfanyl]-N-phenyl-acetamide 
• 204988-95-4 4-(4-Methoxy-phenyl)-5-oxo-2-(2-oxo-propylsulfanyl)-5H-indeno[1,2-b]pyridine-3-carbonitrile 
• 204988-97-6 4-(4-Methoxy-phenyl)-5-oxo-2-(2-oxo-2-phenyl-ethylsulfanyl)-5H-indeno[1,2-b]pyridine-3-carbonitrile 
• 204989-01-5 2-[3-Cyano-4-(4-methoxy-phenyl)-5-oxo-5H-indeno[1,2-b]pyridin-2-ylsulfanyl]-acetamide 
• 204989-19-5 5-(4-Methoxy-phenyl)-1,3-dithioxo-1,2,3,4-tetrahydro-12-thia-2,4,11-triaza-indeno[1,2-b]fluoren-6-one 
• 204989-18-4 5-(4-Methoxy-phenyl)-3-thioxo-3,4-dihydro-2H-12-thia-2,4,11-triaza-indeno[1,2-b]fluorene-1,6-dione 
• 204989-11-7 1-Amino-10-(4-methoxy-phenyl)-9-oxo-9H-3-thia-4-aza-cyclopenta[b]fluorene-2-carboxylic acid ethyl ester 
• 204989-24-2 5-(4-Methoxy-phenyl)-3-methyl-2-oxa-12-thia-4,11-diaza-indeno[1,2-b]fluorene-1,6-dione 
• 204989-13-9 1-Amino-10-(4-methoxy-phenyl)-9-oxo-9H-3-thia-4-aza-cyclopenta[b]fluorene-2-carboxylic acid amide 
• 204989-23-1 1-Amino-10-(4-methoxy-phenyl)-9-oxo-9H-3-thia-4-aza-cyclopenta[b]fluorene-2-carboxylic acid 
• 204989-17-3 1-Amino-10-(4-methoxy-phenyl)-9-oxo-9H-3-thia-4-aza-cyclopenta[b]fluorene-2-carbonitrile 
• 84762-18-5 4-(p-methoxyphenyl)-3-cyano-5-oxoindeno[1,2-b]pyridine-2(1H)-one 
• 204988-87-4 2-Amino-4-(4-methoxy-phenyl)-5-oxo-5H-indeno[1,2-b]pyridine-3-carbonitrile 

Relevant academic research and scientific papers

Synthesis of Indenopyridines and Indenothienopyridines

4-Aryl-3-cyano-5-oxo or (phenylimino)indenopyridin-2thiones 3a-c were prepared from indanone 1 with arylidene cyanothioacetamide or from arylideneindanone 2 with cyanothioacetamide.The corresponding 2-aminoindenopyridine 4 was synthesized from the reaction of 3b with NaN3 in the presence of NH4Cl in DMF.Hydrolysis of 4 using NaOH or H2SO4 gave compounds 6 and 7, respectively.S-Alkylation of 3 with halo compounds afforded derivatives 9a-p, which underwent ring closure with EtONa to produce indenothienopyridines 10a-1.