205238-31-9

Upstream product

• 205238-28-4 1-Benzenesulfonyl-3-(2-tert-butyl-4,5-dihydro-[1,3]dioxepin-5-yl)-1H-indole 
• 205238-30-8 Acetic acid (S)-2-(1-benzenesulfonyl-1H-indol-3-yl)-3-hydroxy-propyl ester 
• 205238-29-5 2-(1-Benzenesulfonyl-1H-indol-3-yl)-propane-1,3-diol 
• 80360-14-1 3-iodo-1-phenylsulfonyl-1H-indole 
• 476682-67-4 1-(1-benzenesulfonyl-1H-indol-3-yl)-2-hydroxy-propan-1-one 
• 99655-68-2 3-bromo-1-phenylsulfonyl indole 
• 1025936-30-4 methanesulfonic acid 2-(1-benzenesulfonyl-1H-indol-3-yl)-1-methyl-2-oxo-ethyl ester 
• 205238-42-2 Acetic acid (R)-2-(1-benzenesulfonyl-1H-indol-3-yl)-3-(toluene-4-sulfonyloxy)-propyl ester 

Downstream Products

• 205238-44-4 Methanesulfonic acid (R)-2-(1-benzenesulfonyl-1H-indol-3-yl)-propyl ester 
• 205238-39-7 (S)-3-(1-Benzenesulfonyl-1H-indol-3-yl)-butyric acid methyl ester 
• 205238-32-0 (S)-3-(1-Benzenesulfonyl-1H-indol-3-yl)-butyronitrile 

Relevant academic research and scientific papers

Pinacol rearrangement for constructing asymmetric centers adjacent to heterocycles

Stereospecific pinacol-type 1,2-shift of electron-rich heterocycles was achieved under organoaluminum-promoted conditions to afford optically pure ketones or alcohols possessing these heterocycles. The method was applied to the asymmetric formal total synthesis of indolmycin.

Chemoenzymatic formal synthesis of (-)-indolmycin

An enantioselective formal total synthesis of indolmycin (1) has been accomplished based on the lipase mediated asymmetric acetylation of the prochiral diol (5).