20541-99-5Relevant academic research and scientific papers
Synthesis method of 2,2'-diamido-N-methyldiethylamine
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Paragraph 0029; 0030; 0031; 0032; 0033; 0034, (2019/03/28)
The invention discloses a synthesis method of 2,2'-diamido-N-methyldiethylamine. The synthesis method is characterized in that acetic anhydride is added dropwise into N-methyldiethanolamine, ripeningis conducted after dropping dropwise adding is completed, and a compound II is obtained; phthalimide is added into the compound II, heating and ripening are conducted after adding is completed, and acompound III is obtained; 6N hydrochloric acid is added into the compound III, then heating and ripening are conducted after adding is completed, and a compound IV is obtained; and sodium methoxide isadded into the compound IV, and ripening at the low temperature is conducted after adding is completed. The technological method for synthesizing high-purity 2,2'-diamido-N-methyldiethylamine has theadvantages of being low in cost, high in yield, simple in purification technology, convenient to operate and suitable for industrialized production, the GC purity of the prepared 2,2'-diamido-N-methyldiethylamine can be as high as 99% or above, and the total yield is 60% or above.
POLYAZACYCLIC COMPOUNDS. PART I. SYNTHESIS OF ARYLSULFONYL DERIVATIVES OF 1,4,7,10-TETRAAZACYCLODODECANE AND 1-OXA-4,7,10-TRIAZACYCLODODECANE SUBSTITUTED AT REQUIRED NITROGEN ATOMS
Sienkiewicz, Juliusz,Goss, Ewa,Stanczak, Andrzej
, p. 77 - 86 (2007/10/02)
A method of preparation of new polyazamacrocyclic compounds substituted at required nitrogen atoms is given based on the example of synthesis of the title derivatives.The method consists in the cyclocondensation of substrates, of which at least one has a tertiary amino group present in the macrocyclic compound.
