205441-87-8

Basic information

• Product Name: 4-[(3R,4R,5S)-3,4-Bis-benzyloxy-5-(tert-butyl-diphenyl-silanyloxymethyl)-pyrrolidin-(2E)-ylidene]-2-((E)-3-hydroxy-2-methyl-propenyl)-4H-oxazol-5-one
• Synonyms: 4-[(3R,4R,5S)-3,4-Bis-benzyloxy-5-(tert-butyl-diphenyl-silanyloxymethyl)-pyrrolidin-(2E)-ylidene]-2-((E)-3-hydroxy-2-methyl-propenyl)-4H-oxazol-5-one
• CAS NO: 205441-87-8
• Molecular Weight: 702.923
• Mol File: 205441-87-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-[(3R,4R,5S)-3,4-Bis-benzyloxy-5-(tert-butyl-diphenyl-silanyloxymethyl)-pyrrolidin-(2E)-ylidene]-2-((E)-3-hydroxy-2-methyl-propenyl)-4H-oxazol-5-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[(3R,4R,5S)-3,4-Bis-benzyloxy-5-(tert-butyl-diphenyl-silanyloxymethyl)-pyrrolidin-(2E)-ylidene]-2-((E)-3-hydroxy-2-methyl-propenyl)-4H-oxazol-5-one(205441-87-8)
• EPA Substance Registry System: 4-[(3R,4R,5S)-3,4-Bis-benzyloxy-5-(tert-butyl-diphenyl-silanyloxymethyl)-pyrrolidin-(2E)-ylidene]-2-((E)-3-hydroxy-2-methyl-propenyl)-4H-oxazol-5-one(205441-87-8)

Safety Data

• Hazardous Substances Data: 205441-87-8(Hazardous Substances Data)

Upstream product

• 205441-84-5 2-((E)-3-Benzyloxymethoxy-2-methyl-propenyl)-4-[(3R,4R,5S)-3,4-bis-benzyloxy-5-(tert-butyl-diphenyl-silanyloxymethyl)-pyrrolidin-(2E)-ylidene]-4H-oxazol-5-one 
• 205441-82-3 benzyl N-[(E)-3-(benzyloxymethoxy)methyl-2-butenoyl]glycinate 
• 205441-83-4 N-[(E)-3-(benzyloxymethoxy)methyl-2-butenoyl]glycine 
• 205441-77-6 2-[(E)-2-(benzyloxymethoxy)methyl-1-propenyl]-4H-oxazol-5-one 
• 205441-80-1 (E)-4-Benzyloxymethoxy-3-methyl-but-2-enoic acid methyl ester 
• 205441-81-2 (E)-3-(benzyloxymethoxy)methyl-2-butenoic acid 
• 13866-57-4 (E)-methyl 4-hydroxy-3-methylbut-2-enoate 
• 205441-85-6 (E)-3-{4-[(3R,4R,5S)-3,4-Bis-benzyloxy-5-(tert-butyl-diphenyl-silanyloxymethyl)-pyrrolidin-(2E)-ylidene]-5-oxo-4,5-dihydro-oxazol-2-yl}-2-methyl-propenal 

Downstream Products

• 205441-88-9 4-[(3R,4R,5S)-3,4-Bis-benzyloxy-5-(tert-butyl-diphenyl-silanyloxymethyl)-pyrrolidin-(2E)-ylidene]-2-((1R,2S)-1,2,3-trihydroxy-2-methyl-propyl)-4H-oxazol-5-one 
• 205441-92-5 4-[(3R,4R,5S)-3,4-dibenzyloxy-5-(methanesulfonyloxy)methylpyrrolidin-2-ylidene]-2-[(2S)-2,3-epoxy-2-methylpropionyl]-4H-oxazol-5-one 
• 205442-05-3 3-Methoxy-5-methyl-naphthalene-1-carboxylic acid (R)-{4-[(3R,4R,5S)-3,4-bis-benzyloxy-5-hydroxymethyl-pyrrolidin-(2E)-ylidene]-5-oxo-4,5-dihydro-oxazol-2-yl}-((S)-2-methyl-oxiranyl)-methyl ester 
• 205441-91-4 4-[(3R,4R,5S)-3,4-Bis-benzyloxy-5-(tert-butyl-diphenyl-silanyloxymethyl)-pyrrolidin-(2E)-ylidene]-2-((S)-2-methyl-oxiranecarbonyl)-4H-oxazol-5-one 
• 205441-90-3 4-[(3R,4R,5S)-3,4-Bis-benzyloxy-5-(tert-butyl-diphenyl-silanyloxymethyl)-pyrrolidin-(2E)-ylidene]-2-[(R)-hydroxy-((S)-2-methyl-oxiranyl)-methyl]-4H-oxazol-5-one 
• 205441-75-4 13-desacetyl-12,13-di-O-benzyloxy-4-O-methyl-carzinophilin 
• 205441-89-0 Methanesulfonic acid (2S,3R)-3-{4-[(3R,4R,5S)-3,4-bis-benzyloxy-5-(tert-butyl-diphenyl-silanyloxymethyl)-pyrrolidin-(2E)-ylidene]-5-oxo-4,5-dihydro-oxazol-2-yl}-2,3-dihydroxy-2-methyl-propyl ester 
• 205442-01-9 3-Methoxy-5-methyl-naphthalene-1-carboxylic acid (S)-[([(3R,4R,5S)-3,4-bis-benzyloxy-5-methanesulfonyloxymethyl-pyrrolidin-(2E)-ylidene]-{1-[1-methoxy-meth-(Z)-ylidene]-2-oxo-propylcarbamoyl}-methyl)-carbamoyl]-((S)-2-methyl-oxiranyl)-methyl ester 
• 205442-04-2 3-Methoxy-5-methyl-naphthalene-1-carboxylic acid (R)-{4-[(3R,4R,5S)-3,4-bis-benzyloxy-5-(tert-butyl-diphenyl-silanyloxymethyl)-pyrrolidin-(2E)-ylidene]-5-oxo-4,5-dihydro-oxazol-2-yl}-((S)-2-methyl-oxiranyl)-methyl ester 
• 228120-05-6 3-Methoxy-5-methyl-naphthalene-1-carboxylic acid (S)-{4-[(3R,4R,5S)-3,4-bis-benzyloxy-5-methanesulfonyloxymethyl-pyrrolidin-(2E)-ylidene]-5-oxo-4,5-dihydro-oxazol-2-yl}-((S)-2-methyl-oxiranyl)-methyl ester 
• 205441-76-5 Methanesulfonic acid (2S,3R,4R)-3,4-bis-benzyloxy-5-[2-[(S)-hydroxy-((S)-2-methyl-oxiranyl)-methyl]-5-oxo-oxazol-(4E)-ylidene]-pyrrolidin-2-ylmethyl ester 

Relevant articles and documents

A stereoselective synthesis of 4-O-methyl-13-desacetyl-12,13-di-o-benzylcarzinophilin

The title synthesis was achieved by the synthetic scheme featuring the following four key steps: i) coupling of the methyl thioimidate with the 2-oxazolin-5-one (5+6→13), ii) construction of the C17-C21 functionality by the use of Sharpless asymmetric dih