2055041-41-1 Usage
Uses
Used in Bioconjugation:
NH-(PEG4-t-butyl ester)2 is used as a bioconjugation agent for the formation of stable covalent bonds between biomolecules and other molecules, such as drugs or imaging agents. The reactivity of the amino group with various functional groups allows for the efficient attachment of different molecules, enhancing their properties and applications.
Used in Drug Delivery Systems:
In the pharmaceutical industry, NH-(PEG4-t-butyl ester)2 is used as a component in the development of drug delivery systems. The PEGylation of drugs using this reagent can improve their solubility, stability, and circulation time in the body, leading to enhanced therapeutic effects and reduced side effects.
Used in Diagnostics:
NH-(PEG4-t-butyl ester)2 is used as a key component in the development of diagnostic tools, such as imaging agents and biosensors. The ability to form stable covalent bonds with various biomolecules allows for the creation of highly specific and sensitive diagnostic agents.
Used in Material Science:
In the field of material science, NH-(PEG4-t-butyl ester)2 is used as a building block for the synthesis of novel materials with tailored properties. The reactivity of the amino group and the deprotection of the t-butyl ester under acidic conditions enable the creation of complex structures with specific functionalities.
Used in Chemical Synthesis:
NH-(PEG4-t-butyl ester)2 is used as an intermediate in the synthesis of various chemical compounds, taking advantage of its unique structure and reactivity. The amino group and t-butyl ester can be used to introduce PEG moieties into different molecules, providing improved properties such as solubility, stability, and biocompatibility.
Check Digit Verification of cas no
The CAS Registry Mumber 2055041-41-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 2,0,5,5,0,4 and 1 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 2055041-41:
(9*2)+(8*0)+(7*5)+(6*5)+(5*0)+(4*4)+(3*1)+(2*4)+(1*1)=111
111 % 10 = 1
So 2055041-41-1 is a valid CAS Registry Number.
2055041-41-1Relevant academic research and scientific papers
Ursuegui, Sylvain,Schneider, Jérémy P.,Imbs, Claire,Lauvoisard, Florian,Dudek, Marta,Mosser, Michel,Wagner, Alain
, p. 8579 - 8584 (2018)
We designed a convergent synthesis pathway that provides access to trifunctional oligoethyleneglycol-amine (OEG-amine) linkers. By applying the reductive coupling of a primary azide to bifunctional OEG-azide precursors, the corresponding symmetrical dialkylamine bearing two homo-functional end chain groups and a central nitrogen was obtained. These building blocks bear minimal structural perturbation compared to the native OEG backbone which makes them attractive for biomedical applications. The NMR investigations of the mechanism process reveal the formation of nitrile and imine intermediates which can react with the reduced free amine form. Additionally, these trifunctional OEG-amine linkers were employed in a coupling reaction to afford branched multifunctional PEG dendrons which are molecularly defined. These discrete PEG-based dendrons (n = 16, 18 and 36) could be useful for numerous applications where multivalency is required.
