205526-52-9

Basic information

• Product Name: (2R,4R)-2-(3-[1,3]Dioxolan-2-yl-propyl)-4-phenyl-3-(2,4,6-trimethoxy-benzyl)-oxazolidine
• Synonyms: (2R,4R)-2-(3-[1,3]Dioxolan-2-yl-propyl)-4-phenyl-3-(2,4,6-trimethoxy-benzyl)-oxazolidine
• CAS NO: 205526-52-9
• Molecular Weight: 443.54
• Mol File: 205526-52-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2R,4R)-2-(3-[1,3]Dioxolan-2-yl-propyl)-4-phenyl-3-(2,4,6-trimethoxy-benzyl)-oxazolidine(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,4R)-2-(3-[1,3]Dioxolan-2-yl-propyl)-4-phenyl-3-(2,4,6-trimethoxy-benzyl)-oxazolidine(205526-52-9)
• EPA Substance Registry System: (2R,4R)-2-(3-[1,3]Dioxolan-2-yl-propyl)-4-phenyl-3-(2,4,6-trimethoxy-benzyl)-oxazolidine(205526-52-9)

Safety Data

• Hazardous Substances Data: 205526-52-9(Hazardous Substances Data)

Upstream product

• 56613-80-0 D-2-phenylglycinol 
• 830-79-5 2,4,6-trimethoxybenzaldehyde 
• 16776-90-2 5-(1,3-dioxolan-2-yl)-1-pentanal 
• 204845-22-7 (R)-N-2,4,6-trimethoxybenzylphenylglycinol 

Downstream Products

• 205526-56-3 (2R,6R,1'R)-N-2'-hydroxy-1'-phenylethyl-2,6-diphenylpiperidine 
• 205526-55-2 (2R)-1-[(1R)-2-hydroxy-1-phenylethyl]-2-phenylpiperidine 
• 205526-54-1 (2R,9R)-2,9-diphenyl-1-aza-4-oxabicyclo[4.3.0]nonane 
• 205526-57-4 (+)-(R,R)-2,6-diphenylpiperidine 
• 205526-59-6 (2S,1'R)-N-2'-hydroxy-1'-phenylethyl-2-methylpiperidine 
• 191470-42-5 (-)-(2'R)-((2S,6S)-2,6-dimethylpiperidin-1-yl)-2'-phenylethanol 
• 5119-88-0 (S)-2-methylpiperidine hydrochloride 
• 191470-45-8 (3R,5S)-5-methyl-3-phenyl-2,3,5,6,7,8-hexahydro-oxazolo[3,2-a]pyridine 
• 3466-80-6 (R)-(+)-6-phenylpiperidine 
• 205526-53-0 (1R,1'R)-2-[N-(2,4,6-trimethoxybenzyl)-N-2'-hydroxy-1'-phenylethylamino]-5,5-ethylenedioxy-1-phenylpentane 
• 205526-58-5 (R)-2-[((S)-4-[1,3]Dioxolan-2-yl-1-methyl-butyl)-(2,4,6-trimethoxy-benzyl)-amino]-2-phenyl-ethanol 

Relevant articles and documents

Facile diastereoselective reactions of chiral 1,3-oxazolidines with grignard reagents; asymmetric syntheses of 2-substituted and 2,6-disubstituted piperidines

(S)- and (R)-2-Phenylpiperidines, (S)- and (R)-2-methylpiperidines, meso- and (2R, 6R)-2,6-diphenylpiperidines, and meso- and (25, 65)-2,6-dimethylpiperidines were synthesized asymmetrically starting from the diastereoselective addition of Grignard reagents to chiral 1,3-oxazolidines, converting of 1-aza-4-oxabicyclo[4.3.0]nonane derivatives as pivotal intermediates.