205596-46-9Relevant academic research and scientific papers
A highly efficient synthesis of 1-methyl-, 1-benzyl-, and 1-phenyl-1,2,3,4-tetrahydroisoquinolines by a modified pummerer reaction
Shinohara, Tatsumi,Takeda, Akira,Toda, Jun,Terasawa, Noriyo,Sano, Takehiro
, p. 555 - 565 (2007/10/03)
(±)-1-Methyl- (13b), (±)-1-benzyl- (13c), and (±)-1-phenyl- (13d)-1,2,3,4-tetrahydroisoquinolines, which are supposed to participate in the pathogenesis of Parkinson's disease, were prepared by using a modified Pummerer reaction as a key step in excellent overall yields from the commercially available ketones (4b-c).
