205688-81-9Relevant academic research and scientific papers
Synthesis of Bis-Thiazolidinones Using Chitosan-attached Nano-CuFe2O4 as an Efficient and Retrievable Heterogeneous Catalyst
Safaei-Ghomi, Javad,Shahbazi-Alavi, Hossein,Nazemzadeh, Seyed Hadi
, p. 1213 - 1219 (2017)
The preparation of bis-thiazolidinones has been achieved by a one-pot condensation reaction of araldehydes, ethylenediamine, and 2-mercaptoacetic acid in the presence of nano-CuFe2O4@chitosan under reflux conditions in toluene. The c
Nano-colloidal silica-tethered polyhedral oligomeric silsesquioxanes with eight branches of 3-aminopropyltriethoxysilane as high-performance catalyst for the preparation of bis-thiazolidinones under ultrasonic conditions
Safaei-Ghomi, Javad,Nazemzadeh, Seyed Hadi,Shahbazi-Alavi, Hossein
, p. 927 - 932 (2017/12/15)
We report a class of organic-inorganic hybrid material based on nano-colloidal silica-tethered polyhedral oligomeric silsesquioxanes with eight branches of 3-aminopropyltriethoxysilane [nano-colloidal silica@APTPOSS (a series of polyhedral oligomeric sils
Nano-CdZr4(PO4)6 as a reusable and robust catalyst for the synthesis of bis-thiazolidinones by a multicomponent reaction of aldehydes, ethylenediamine and thioglycolic acid
Safaei-Ghomi, Javad,Nazemzadeh, Seyed Hadi,Shahbazi-Alavi, Hossein
, p. 195 - 205 (2017/03/08)
Nano-CdZr4(PO4)6 has been used as an efficient catalyst for the preparation of bis-thiazolidinones by pseudo-five-component reaction of aldehydes, ethylenediamine and thioglycolic acid under reflux conditions in toluene. T
Synthesis and spectral data of new 1,2-bis-(2-hetaryl-4-oxothiazolidin-3- yl)ethanes and 1,4-bis-(2-hetaryl-4-oxothiazolidin-3-yl)butanes
Kouznetsov, Vladimir V.,Amado, Diego F.,Bahsas, Ali,Amaro-Luis, Juan
, p. 447 - 452 (2007/10/03)
New α,ω-bis-(2-hetaryl-4-oxothiazolidin-3-yl)alkanes were prepared via a common two step procedure using N,N-bis-hetarylidenamines condensation with α-mercaptoacetic acid. The used bis-aldimines were obtained from reaction between ethylenediamine or putrescine and benzaldehyde or the isomeric pyridinecarboxyaldehydes. The bis-(2-phenyl-4-oxothiazolidin-3-yl) alkanes were prepared by one-pot three component reaction of diamine, aldehyde and α-mercaptoacetic acid under very mild conditions.
3,3'-Di(1,3-triazolidine-4-one) system. V. Synthesis and pharmacological properties of 3,3' (1,2-ethanediyl)bis-(2-heteroaryl-1,3-thiazolidine-4-one) derivatives
Previtera,Vigorita,Basile,Fenech,Trovato,Occhiuto,Monforte,Barbera
, p. 569 - 579 (2007/10/02)
A class of anti-inflammatory, analgesic and histamine H1- and H2-receptor antagonists the 2,2'-dihetero-arylbisthiazolidinones and their 1,1'-disulfones, obtained as [RR, SS] and [RS, SR] isomers, is described. The heteroaryl substitution at 2 and 2' carbons generally improves the pharmacological activities with respect to those of the previously studied 2,2'-diaryl analogues. In particular the 2,2'-dithienyl derivatives exhibit analgesic properties and, as [RS, SR] isomers 6b, 11b, 12b H2-histamine receptor antagonism as well. The most effective acute anti-inflammatory agents appear to be the 2,2'-di(3-pyridyl) compounds 8a, 8b, 14a, 14b which also display analgesic activity. Moreover, an H1-histamine receptor antagonism is almost selectively exerted by the 2,2'-di(2-pyridyl) derivatives 7a, 7b, 13a, 13b. The relationships between the assessed activities and the chirality and/or the sulfur oxidation state of the molecules are discussed. The anti-cancer potential was also evaluated against P 388 murine lymphocytic leukemia; however, the results were not significant.
