205746-52-7Relevant academic research and scientific papers
Pharmacophoric requirements for cannabinoid side chains: Multiple bond and C1'-substituted Δ8-tetrahydrocannabinols
Papahatjis,Kourouli,Abadji,Goutopoulos,Makriyannis
, p. 1195 - 1200 (1998)
Accumulated evidence indicates that within the cannabinoid structure the aliphatic side chain plays a pivotal role in determining cannabimimetic activity. We describe the synthesis and affinities for the CB1 and CB2 receptors of a series of novel Δ8
