2059-77-0

Upstream product

• 75-15-0 carbon disulfide 
• 540-37-4 p-aminoiodobenzene 
• 463-71-8 thiophosgene 
• 2059-76-9 4-iodophenyl isothiocyanate 

Downstream Products

• 2059-76-9 4-iodophenyl isothiocyanate 
• 726-43-2 bis-(4-iodo-phenyl)-carbodiimide 
• 52476-95-6 3-(4-iodo-phenyl)-2-(4-iodo-phenylimino)-thiazolidin-4-one 
• 90765-13-2 (4-iodo-phenyl)-thiocarbamic acid O-ethyl ester 

Relevant academic research and scientific papers

Di-tert-butyl peroxide (DTBP)-mediated synthesis of symmetrical N,N′-disubstituted urea/thiourea motifs from isothiocyanates in water

ABATRACT: A direct approach to N,N′-disubstituted urea/thiourea from the self-condensation reactions of isothiocyanates in water has been developed. This access tolerated a wide range of functional groups on the aromatic ring, providing a practical and environment-friendly process to N,N′-disubstituted urea/thiourea in moderate to excellent yields from safe and easily available starting materials. A plausible mechanism of the desulfurization self-condensation reaction for urea was also proposed and the role of di-tert-butyl peroxide (DTBP) and copper catalyst in the present strategy was demonstrated with the help of ESI mass spectrometry of intermediate studies.

A highly efficient one-pot method for the synthesis of thioureas and 2-imino-4-thiazolidinones under microwave conditions

A one-pot synthesis of symmetrical and unsymmetrical substituted thioureas and 2-imino-4-thiazolidinones from simple starting materials under microwave irradiation and solventless conditions without base additives is presented. Various di- and trisubstituted thioureas are obtained in good yields in a few minutes. The sequential, three-component, one-pot synthesis of 2-imino-4-thiazolidinone derivatives is also studied, with satisfactory results obtained.