205984-77-6

Basic information

• Product Name: 3-CHLORO-3-(4-FLUOROPHENYL)ACRYLONITRILE
• Synonyms: BUTTPARK 91\18-16;3-CHLORO-3-(4-FLUOROPHENYL)ACRYLONITRILE;(Z)-3-Chloro-3-(4-fluorophenyl)acrylonitrile
• CAS NO: 205984-77-6
• Molecular Formula: C₉H₅ClFN
• Molecular Weight: 181.59
• Mol File: 205984-77-6.mol
• Article Data: 4

Chemical Properties

• Melting Point: 90 °C
• Boiling Point: 275.1°C at 760 mmHg
• Flash Point: 120.2°C
• Appearance: /
• Density: 1.272g/cm³
• Vapor Pressure: 0.00518mmHg at 25°C
• Refractive Index: 1.55
• CAS DataBase Reference: 3-CHLORO-3-(4-FLUOROPHENYL)ACRYLONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-CHLORO-3-(4-FLUOROPHENYL)ACRYLONITRILE(205984-77-6)
• EPA Substance Registry System: 3-CHLORO-3-(4-FLUOROPHENYL)ACRYLONITRILE(205984-77-6)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• Hazardous Substances Data: 205984-77-6(Hazardous Substances Data)

Usage

InChI:InChI=1/C9H5ClFN/c10-9(5-6-12)7-1-3-8(11)4-2-7/h1-5H/b9-5+

Upstream product

• 55338-97-1 β-chloro-β-(4-fluorophenyl)acrylaldehyde 
• 403-42-9 1-(4-fluorophenyl)ethanone 
• 68-12-2 N,N-dimethyl-formamide 

Downstream Products

• 215928-68-0 6-(4-fluorophenyl)thieno[3,2-d]pyrimidin-4(3H)-one 
• 175137-08-3 5-(4-fluorophenyl)-3-aminothiophene-2-carboxylic acid methyl ester 
• 4640-67-9 3-(4-fluorophenyl)-3-oxopropionitrile 
• 925005-35-2 5-(4-fluorophenyl)-3-aminoisoxazole 
• 874479-18-2 (Z)-3-(4-fluorophenyl)-3-(4-methanesulfonylphenyl)acrylonitrile 
• 126418-03-9 N-[5-(4-Fluoro-phenyl)-2-methyl-2H-pyrazol-3-yl]-4-methyl-benzenesulfonamide 
• 126417-95-6 N-[5-(4-Fluoro-phenyl)-1-methyl-1H-pyrazol-3-yl]-4-methyl-benzenesulfonamide 
• 126417-81-0 (3-(4-fluorophenyl)-1-methyl-1H-5-pyrazolyl)amine 
• 120698-04-6 3-Amino-5--1-methyl-pyrazol 

Relevant articles and documents

Novel benzenesulfonamide-bearing pyrazoles and 1,2,4-thiadiazoles as selective carbonic anhydrase inhibitors

Two series comprising 20 novel benzenesulfonamides bearing thioureido-linked pyrazole 8 and amino-1,2,4-thiadiazole 10 were synthesized and assayed as human carbonic anhydrase (hCA) inhibitors against isoforms I and II as well as the tumor-associated isof

One-pot synthesis of 2-substituted thieno[3,2-b]indoles from 3-aminothiophene-2-carboxylates through in situ generated 3-aminothiophenes

A convenient protocol for one-pot synthesis of thieno[3,2-b]indoles, bearing aromatic, thien-2-yl or styryl fragments at C-2 position, from easily accessible 5-substituted 3-aminothiophene-2-carboxylates using the Fischer indolization reaction, was develo