80998-91-0Relevant academic research and scientific papers
Regiospecific C-N photocyclization of 2-styrylquinolines
Gulakova, Elena N.,Berdnikova, Daria V.,Aliyeu, Tseimur M.,Fedorov, Yuri V.,Godovikov, Ivan A.,Fedorova, Olga A.
, p. 5533 - 5537 (2014/07/08)
Regiospecific C-N photocyclization of 2-styrylquinolines resulting in formation of potentially biologically active quino[1,2-a]quinolizinium derivatives was investigated. The presence of strong electron-donating groups in the phenyl ring reveals to be a crucial factor managing photocyclization effectiveness. Introduction of a crown ether moiety allows changing the photoreaction parameters by means of complexation with Mg(ClO4) 2.
Br?nsted acid catalyzed synthesis of 1,3-di(2-quinolyl)propane derivatives via tandem C(sp3)-H functionalization
Jin, Jia-Jia,Wang, Dong-Chao,Niu, Hong-Ying,Wu, Shan,Qu, Gui-Rong,Zhang, Zhong-Bo,Guo, Hai-Ming
, p. 6579 - 6584 (2013/07/25)
A novel protocol for Br?nsted acid catalyzed reaction of 2-methyl azaarenes and aromatic aldehyde to give 1,3-di(2-quinolyl)propane derivatives through tandem C(sp3)-H bond functionalization has been developed. This approach provides a new access to a variety of 1,3-di(2-quinolyl)propane derivatives, which are potentially of great importance in pharmaceuticals and ligand fields.
A catalyst-free benzylic C-H bond olefination of azaarenes for direct mannich-like reactions
Yan, Yizhe,Xu, Kun,Fang, Yang,Wang, Zhiyong
scheme or table, p. 6849 - 6855 (2011/10/04)
A highly efficient synthesis of trans-alkenylazaarene under catalyst-free conditions was developed via the addition of methylazaarenes to N-sulfonyl aldimines and a subsequent C-N elimination in situ. A one-pot procedure for this addition-elimination was also developed. The reaction could tolerate a broad substrate scope and give the corresponding alkenylazaarenes in high yields.
