206060-45-9

Basic information

• Product Name: FMOC-L-PHE(4-CH2-SO3H)
• Synonyms: FMOC-L-PHE(4-CH2-SO3H);N-Fmoc-L-4-sulfomethyl-Phenylalanine
• CAS NO: 206060-45-9
• Molecular Formula: C₂₅H₂₃NO₇S
• Molecular Weight: 481.52
• Mol File: 206060-45-9.mol
• Article Data: 2

Chemical Properties

• Melting Point: >270 °C
• Appearance: /
• Density: 1.423±0.06 g/cm3(Predicted)
• PKA: 1.42±0.50(Predicted)
• CAS DataBase Reference: FMOC-L-PHE(4-CH2-SO3H)(CAS DataBase Reference)
• NIST Chemistry Reference: FMOC-L-PHE(4-CH2-SO3H)(206060-45-9)
• EPA Substance Registry System: FMOC-L-PHE(4-CH2-SO3H)(206060-45-9)

Safety Data

• Hazardous Substances Data: 206060-45-9(Hazardous Substances Data)

Upstream product

• 82911-69-1 N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide 
• 945245-47-6 N-(fluorenyl-9-methoxycarbonyl)-L-(p-sulfomethyl)phenylalanine methyl ester 
• 1146758-11-3 C₂₇H₂₄Cl₃NO₇S 
• 216774-50-4 N-tert-butyloxycarbonyl-(p-hydroxymethyl)-L-phenylalanine methyl ester 
• 15742-88-8 L-(p-hydroxymethyl)phenylalanine 
• 298693-79-5 methyl (S)-2-((tert-butoxycarbonyl)amino)-3-(4-cyanophenyl)propanoate 
• 82911-79-3 N-(fluorenyl-9-methoxycarbonyl)-L-tyrosine methyl ester 
• 15742-86-6 N-Acetyl (4-hydroxymethyl)-DL-phenylalanine 
• 112766-18-4 methyl N-(tert-butoxycarbonyl)-O-[(trifluoromethyl)sulfonyl]-L-tyrosinate 
• 945245-46-5 N-(fluorenyl-9-methoxycarbonyl)-L-(p-bromomethyl)phenylalanine methyl ester 
• 945245-45-4 N-(fluorenyl-9-methoxycarbonyl)-L-(p-hydroxymethyl)phenylalanine methyl ester 
• 945245-50-1 N-(fluorenyl-9-methoxycarbonyl)-L-p-formyl-phenylalanine methyl ester 
• 298693-92-2 N-(fluorenyl-9-methoxycarbonyl)-L-O-trifluoromethylsulfonyl-tyrosine methyl ester 
• 266999-30-8 C₁₅H₂₁NO₇S 

Downstream Products

• 945245-54-5 N-(fluorenyl-9-methoxycarbonyl)-L-(p-sulfomethyl)phenylalanyl-L-(4-O-benzyl)-aspartic acid α-tert-butyl ester 
• 1146758-19-1 C₅₃H₇₁Cl₆N₉O₂₂S₂ 

Relevant articles and documents

Trichloroethyl group as a protecting group for sulfonates and its application to the synthesis of a disulfonate analog of the tyrosine sulfated PSGL-143-50 peptide

The trichloroethyl (TCE) group is shown to be a viable protecting group for sulfonates. TCE-protected sulfonates were found to be particularly stable to acid, a key characteristic that led to a straightforward enantioselective synthesis of L-FmocPhe(p-CH