15742-86-6

Basic information

• Product Name: N-Acetyl (4-hydroxymethyl)-DL-phenylalanine
• Synonyms: N-Acetyl (4-hydroxymethyl)-DL-phenylalanine
• CAS NO: 15742-86-6
• Molecular Weight: 237.255
• Mol File: 15742-86-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-Acetyl (4-hydroxymethyl)-DL-phenylalanine(CAS DataBase Reference)
• NIST Chemistry Reference: N-Acetyl (4-hydroxymethyl)-DL-phenylalanine(15742-86-6)
• EPA Substance Registry System: N-Acetyl (4-hydroxymethyl)-DL-phenylalanine(15742-86-6)

Safety Data

• Hazardous Substances Data: 15742-86-6(Hazardous Substances Data)

Upstream product

• 99-75-2 4-methyl-benzoic acid methyl ester 
• 15720-16-8 4-(bromomethyl)benzyl alcohol acetate 
• 2417-72-3 Methyl 4-(bromomethyl)benzoate 
• 114791-23-0 diethyl <4-(hydroxymethyl)benzyl>acetamidomalonate 
• 71831-21-5 4-(bromomethyl)benzyl alcohol 
• 6232-88-8 4-bromomethylbenzoic Acid 
• 17268-36-9 Diethyl <4-(acetoxymethyl)benzyl>acetamidomalonate 

Downstream Products

• 182617-53-4 2-[4-(2-Acetylamino-2-benzyloxycarbonyl-ethyl)-benzyl]-4,4-dimethoxy-3-oxo-pentanoic acid methyl ester 
• 132067-40-4 N-Acetyl (4-diethoxyphosphonomethyl)-DL-phenylalanine 
• 120667-17-6 4-(Phosphonomethyl)-DL-phenylalanine 
• 132067-39-1 N-Acetyl (4-bromomethyl)-DL-phenylalanine methyl ester 
• 216774-50-4 N-tert-butyloxycarbonyl-(p-hydroxymethyl)-L-phenylalanine methyl ester 
• 216774-45-7 methyl 2-(S)-((tert-butoxycarbonyl)amino)-3-(4'-formyl-phenyl)propanoate 
• 160916-46-1 N-boc-4-hydroxymethylphenylalanine 
• 206060-45-9 N-(fluorenyl-9-methoxycarbonyl)-L-(p-sulfomethyl)phenylalanine 
• 945245-47-6 N-(fluorenyl-9-methoxycarbonyl)-L-(p-sulfomethyl)phenylalanine methyl ester 
• 945245-46-5 N-(fluorenyl-9-methoxycarbonyl)-L-(p-bromomethyl)phenylalanine methyl ester 
• 945245-45-4 N-(fluorenyl-9-methoxycarbonyl)-L-(p-hydroxymethyl)phenylalanine methyl ester 
• 945245-54-5 N-(fluorenyl-9-methoxycarbonyl)-L-(p-sulfomethyl)phenylalanyl-L-(4-O-benzyl)-aspartic acid α-tert-butyl ester 
• 15742-88-8 L-(p-hydroxymethyl)phenylalanine 
• 132067-38-0 N-Acetyl (4-hydroxymethyl)-DL-phenylalanine methyl ester 

Relevant articles and documents

α-Dicarbonyls as 'non-charged' arginine-directed affinity labels. Novel synthetic routes to α-dicarbonyl analogs of the pp60(c-src) SH2 domain-targeted phosphopeptide Ac-Tyr(OPO3H2)-Glu-Glu-Ile-Glu

The phosphopeptide 1 is a potent inhibitor of pp60(c-src) SH2 domain mediated phosphoprotein interactions (IC50 ≤ 0.5 μM), but lacks cell permeability. The syntheses of its less charged analogs 2 and 3 are described, in which the arginine-binding phosphate group has been substituted with uncharged α-dicarbonyl moieties. The chemistry described here may be of general use for the synthesis of other α-dicarbonyl compounds.