206186-94-9Relevant academic research and scientific papers
Chiron approach to the total synthesis of Amaryllidaceae alkaloid (+)-lycoricidine
Saidhareddy, Puli,Shaw, Arun K.
, p. 6773 - 6779 (2017/10/30)
A highly stereoselective total synthesis of Amaryllidaceae alkaloid starting from α-D-galactopyranoside has been described. The salient features of this total synthesis are Ferrier carbocyclization reaction for the synthesis of ring A and Suzuki Miyaura c
Mechanistic studies on the stereoselective formation of β-mannosides from mannosyl iodides using α-deuterium kinetic isotope effects
El-Badri, Mohamed H.,Willenbring, Dan,Tantillo, Dean J.,Gervay-Hague, Jacquelyn
, p. 4663 - 4672 (2008/02/10)
(Chemical Equation Presented) Stereoselective synthesis of β-mannosides is one of the most challenging linkages to achieve in carbohydrate chemistry. Both the anomeric effect and the C2 axial substituent favor the formation of the axial glycoside (α-produ
Synthesis and evaluation of a mechanism-based inhibitor of KDO8P synthase
Belakhov, Valery,Dovgolevsky, Ekaterina,Rabkin, Emilia,Shulami, Smadar,Shoham, Yuval,Baasov, Timor
, p. 385 - 392 (2007/10/03)
The enzyme 3-deoxy-D-manno-2-octulosonate-8-phosphate (KDO8P) synthase catalyzes the condensation reaction between phosphoenolpyruvate (PEP) and D-arabinose 5-phosphate (A5P) to produce KDO8P and inorganic phosphate. In attempts to investigate the lack of
