20619-13-0

Basic information

• Product Name: N,N-didemethylchlorpheniramine
• Synonyms: N,N-didemethylchlorpheniramine;3-(4-Chlorophenyl)-3-(2-pyridyl)propan-1-amine
• CAS NO: 20619-13-0
• Molecular Formula: C₁₄H₁₅ClN₂
• Molecular Weight: 246.74
• Mol File: 20619-13-0.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 374°Cat760mmHg
• Flash Point: 180°C
• Appearance: /
• Density: 1.166g/cm³
• Vapor Pressure: 8.6E-06mmHg at 25°C
• Refractive Index: 1.589
• CAS DataBase Reference: N,N-didemethylchlorpheniramine(CAS DataBase Reference)
• NIST Chemistry Reference: N,N-didemethylchlorpheniramine(20619-13-0)
• EPA Substance Registry System: N,N-didemethylchlorpheniramine(20619-13-0)

Safety Data

• Hazardous Substances Data: 20619-13-0(Hazardous Substances Data)

Usage

InChI:InChI=1/C14H15ClN2/c15-12-6-4-11(5-7-12)13(8-9-16)14-3-1-2-10-17-14/h1-7,10,13H,8-9,16H2

Upstream product

• 109-09-1 2-chloropyridine 
• 4350-41-8 2-(4-chlorobenzyl)pyridine 
• 59067-07-1 3-bromopropinaldehyde diethyl acetal 
• 58498-12-7 4-(2-Pyridinylmethyl)phenylamine 
• 104-83-6 1-Chloro-4-(chloromethyl)benzene 
• 109-04-6 2-bromo-pyridine 
• 160911-84-2 1-(4-chlorophenyl-1-(2-pyridyl))ehylene 
• 140-53-4 p-chlorobenzyl cyanide 
• 5005-37-8 2-(4-chlorophenyl)-2-(pyridin-2-yl)acetonitrile 
• 405551-69-1 3-(4-chloro-phenyl)-3-pyridin-2-yl-acrylonitrile 
• 6318-51-0 2-(4-chlorobenzoyl)pyridine 
• 405551-70-4 3-(4-chlorophenyl)-3-(pyridin-2-yl)propanenitrile 
• 122376-81-2 2-(4-Chloro-phenyl)-4-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-2-pyridin-2-yl-butyronitrile 

Downstream Products

• 405551-74-8 2-[1-(4-chloro-phenyl)-3-isocyanato-propyl]-pyridine 
• 405551-80-6 N-[3-(4-chloro-phenyl)-3-pyridin-2-yl-propyl]-3-(1-trityl-1H-imidazol-4-yl)-propionamide 
• 405551-76-0 N-[3-(4-chloro-phenyl)-3-pyridin-2-yl-propyl]-4-(1-trityl-1H-imidazol-4-yl)-butyramidine 
• 113-92-8 chlorphenamine maleate 
• 405551-87-3 1-[3-(4-chloro-phenyl)-3-pyridin-2-yl-propyl]-3-[4-(1-trityl-1H-imidazol-4-yl)-butyl]-urea 
• 405551-81-7 N-[3-(4-chloro-phenyl)-3-pyridin-2-yl-propyl]-N-methyl-3-(1-trityl-1H-imidazol-4-yl)-propionamide 
• 725738-26-1 [3-(4-chloro-phenyl)-3-pyridin-2-yl-propyl]-[3-(1-trityl-1H-imidazol-4-yl)-propyl]-amine 
• 725738-46-5 [3-(4-chloro-phenyl)-3-pyridin-2-yl-propyl]-methyl-[3-(1-trityl-1H-imidazol-4-yl)-propyl]-amine 

Relevant articles and documents

1/10-water maleic acid chlorpheniramine compound and pharmaceutical composition thereof (by machine translation)

The invention discloses-water 1/10 maleic acid chlorphenamine maleate compound and a preparation method thereof, wherein the compound is measured by a powder X-2 θ ± 0.2° ray diffraction method and shows characteristic 12.4 ° diffraction peaks 18.9 ° 13.1 ° at 20.3 ° 19.4 ° diffraction 21.6 ° 22.0 ° angles in 24.2 ° 24.7 °, 25.1 ° 26.3 ° and 30.1 ° 32.3 °. 1/10 Water prepared by the method has the advantages of good stability, high purity, good solubility and high bioavailability of the preparation, and is simple in process, high in yield, high in repeatability and suitable for industrial production. (by machine translation)

Identification of a dual histamine H1/H3 receptor ligand based on the H1 antagonist chlorpheniramine

Combining the first generation H1 antihistamine chlorpheniramine (1) with H3 ligands of the alkylamine type has led to the identification of compound 9d, a dual ligand of both the H1 and H3 receptors.