405551-69-1Relevant articles and documents
Copper-Catalyzed C-H Stereoselective Cyanation of Alkenes by Using an α-Iminonitrile as a Cyanating Reagent
Chen, Zhen-Bang,Gao, Qing-Qing,Liu, Kui,Zhu, Yong-Ming
supporting information, p. 203 - 206 (2019/01/14)
The first copper-catalyzed cyanation through alkene C-H bond activation by using an α-iminonitrile as a cyanating agent has been realized. The approach efficiently constructs acrylonitriles in good yields with the advantages of high regioselectivity, cost
Identification of a dual histamine H1/H3 receptor ligand based on the H1 antagonist chlorpheniramine
Aslanian, Robert,Mutahi, Mwangi Wa,Shih, Neng-Yang,Piwinski, John J.,West, Robert,Williams, Shirley M.,She, Susan,Wu, Ren-Long,Hey, John A.
, p. 1959 - 1961 (2007/10/03)
Combining the first generation H1 antihistamine chlorpheniramine (1) with H3 ligands of the alkylamine type has led to the identification of compound 9d, a dual ligand of both the H1 and H3 receptors.