Cas 206192-46-3,3-[benzyl-(4-methoxy-benzenesulfonyl)-amino]-thiophene-2-carboxylic acid methyl ester

206192-46-3

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Basic information

Product Name: 3-[benzyl-(4-methoxy-benzenesulfonyl)-amino]-thiophene-2-carboxylic acid methyl ester
Synonyms: 3-[benzyl-(4-methoxy-benzenesulfonyl)-amino]-thiophene-2-carboxylic acid methyl ester
CAS NO:206192-46-3
Molecular Formula:
Molecular Weight: 417.507
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: 3-[benzyl-(4-methoxy-benzenesulfonyl)-amino]-thiophene-2-carboxylic acid methyl ester(CAS DataBase Reference)
NIST Chemistry Reference: 3-[benzyl-(4-methoxy-benzenesulfonyl)-amino]-thiophene-2-carboxylic acid methyl ester(206192-46-3)
EPA Substance Registry System: 3-[benzyl-(4-methoxy-benzenesulfonyl)-amino]-thiophene-2-carboxylic acid methyl ester(206192-46-3)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 206192-46-3(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 206192-46-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,0,6,1,9 and 2 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 206192-46:
(8*2)+(7*0)+(6*6)+(5*1)+(4*9)+(3*2)+(2*4)+(1*6)=113
113 % 10 = 3
So 206192-46-3 is a valid CAS Registry Number.

206192-46-3Upstream product

206192-46-3Downstream Products

206192-50-9 3-[benzyl-(4-methoxy-benzenesulfonyl)-amino]-thiophene-2-carboxylic acid

206192-46-3Relevant academic research and scientific papers

HETEROARYL ACETYLENIC SULFONAMIDE AND PHOSPHINIC ACID AMIDE HYDROXAMIC ACID TACE INHIBITORS

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Page 21, (2010/02/05)

Compounds of formula (I) are useful in treating disease conditions mediated by TNF- alpha such as rheumatoid arthritis, osteoarthritis, sepsis, AIDS, ulcerative colitis, multiple sclerosis, Crohn's disease and degenerative cartilage loss.

THE PREPARATION AND USE OF ORTHO-SULFONAMIDO HETEROARYL HYDROXAMIC ACIDS AS MATRIX METALLOPROTEINASE AND TACE INHIBITORS

-

, (2008/06/13)

The present invention relates to the discovery of novel, low molecular weight, non-peptide inhibitors of matrix metalloproteinases (e.g. gelatinases, stromelysins and collagenases) and TNF- alpha converting enzyme (TACE, tumor necrosis factor- alpha conve

Heteroaryl and cycloalkyl sulfonamide hydroxamic acid inhibitors of matrix metalloproteinases

Levin, Jeremy I.,Gu, Yansong,Nelson, Frances C.,Zask, Arie,DiJoseph, John F.,Sharr, Michele A.,Sung, Amy,Jin, Guixian,Cowling, Rebecca,Chanda, Pranab,Cosmi, Scott,Hsiao, Chu-Lai,Edris, Wade,Wilhelm, James,Killar, Loran M.,Skotnicki, Jerauld S.

, p. 239 - 242 (2007/10/03)

Heteroaryl and cycloalkyl sulfonamide-hydroxamic acid MMP inhibitors were investigated. Of these, the pyridyl analogue 2 is the most potent and selective inhibitor of MMP-9 and MMP-13 in vitro.

Heteroaryl acetylenic sulfonamide and phosphinic acid amide hydroxamic acid tace inhibitors

-

, (2008/06/13)

Compounds of the formula: are useful in treating disease conditions mediated by TNF-α such as rheumatoid arthritis, osteoarthritis, sepsis, AIDS, ulcerative colitis, multiple sclerosis, Crohn's disease and degenerative cartilage loss.

PREPARATION AND USE OF ORTHOSULFONAMIDO HETEROARYL HYDROXAMIC ACIDS AS MATRIX METALLOPROTEINASE AND TACE INHIBITIORS

-

, (2008/06/13)

The present invention relates to the discovery of novel, low molecular weight, non-peptide inhibitors of matrix metalloproteinases (e. g. gelatinases, stromelysins and collagenases) and TNF-α converting enzyme (TACE, tumor necrosis factor-α converting enz

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