206192-65-6Relevant academic research and scientific papers
Heteroaryl and cycloalkyl sulfonamide hydroxamic acid inhibitors of matrix metalloproteinases
Levin, Jeremy I.,Gu, Yansong,Nelson, Frances C.,Zask, Arie,DiJoseph, John F.,Sharr, Michele A.,Sung, Amy,Jin, Guixian,Cowling, Rebecca,Chanda, Pranab,Cosmi, Scott,Hsiao, Chu-Lai,Edris, Wade,Wilhelm, James,Killar, Loran M.,Skotnicki, Jerauld S.
, p. 239 - 242 (2007/10/03)
Heteroaryl and cycloalkyl sulfonamide-hydroxamic acid MMP inhibitors were investigated. Of these, the pyridyl analogue 2 is the most potent and selective inhibitor of MMP-9 and MMP-13 in vitro.
