2063-74-3

Basic information

• Product Name: 4,4'-(1,1'-oxybis(ethane-1,1-diyl))bis(fluorobenzene)
• Synonyms: 4,4'-(1,1'-oxybis(ethane-1,1-diyl))bis(fluorobenzene)
• CAS NO: 2063-74-3
• Molecular Weight: 262.299
• Mol File: 2063-74-3.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 4,4'-(1,1'-oxybis(ethane-1,1-diyl))bis(fluorobenzene)(CAS DataBase Reference)
• NIST Chemistry Reference: 4,4'-(1,1'-oxybis(ethane-1,1-diyl))bis(fluorobenzene)(2063-74-3)
• EPA Substance Registry System: 4,4'-(1,1'-oxybis(ethane-1,1-diyl))bis(fluorobenzene)(2063-74-3)

Safety Data

• Hazardous Substances Data: 2063-74-3(Hazardous Substances Data)

Upstream product

• 775-12-2 diphenylsilane 
• 403-42-9 1-(4-fluorophenyl)ethanone 
• 617-86-7 triethylsilane 
• 67-56-1 methanol 
• 403-41-8 1-(4-Fluorophenyl)ethanol 

Relevant articles and documents

Synthetic method of borane-catalyzed symmetric ether

The invention provides a borane-catalyzed symmetric ether synthesis method, which is characterized in that alcohol is used as a raw material, and under the catalysis of B(2,6-Cl2C6H3) (p-HC6F4) 2, etherification reaction is carried out through intermolecular dehydration to generate ether. The reaction process is simple, mild, pollution-free and efficient.

Ether formation through reductive coupling of ketones or aldehydes catalyzed by a mesoionic carbene iridium complex

An iridium(iii) Cp? complex containing a triazolylidene-pyridyl C,N-bidentate-coordinating ligand is a very powerful catalyst for the transformation of ketones and aldehydes into symmetrical ethers. This highly efficient reductive coupling proceeds immediately at room temperature and at a low catalyst loading (0.1 mol%) when Ph2SiH2 is used as an additive. Aromatic carbonyl substrates react faster than aliphatic ketones or aldehydes, and the substrate scope suggests some functional group tolerance. Likewise, the condensation of alcohols to symmetrical ethers is catalyzed by this triazolylidene iridium complex, though ether formation is an order of magnitude slower than when starting from the analogous ketone or aldehyde as a substrate, suggesting that alcohols are not potential intermediates in the reductive coupling process. Prolonged reactions or modification of the silane additive lead to ether cleavage and dehydration, thus affording the corresponding olefin. Mechanistic insights and in particular the different reactivities of alcohols and ketones have been exploited to develop a synthetic methodology for the iridium-catalyzed formation of unsymmetrical methyl ethers (R-OMe) in good yields.

Direct halogenation of alcohols with halosilanes under catalyst- and organic solvent-free reaction conditions

A chemoselective method for the direct halogenation of different types of alcohols with halosilanes under catalyst- and solvent-free reaction conditions (SFRC) is reported. Various primary, secondary and tertiary benzyl alcohols and tertiary alkyl alcohols were directly transformed to the corresponding benzyl and alkyl halides, respectively, using chlorotrimethylsilane (TMSCl) and bromotrimethylsilane (TMSBr).