206347-33-3

Upstream product

• 608-33-3 2,6-dibromophenol 
• 109-64-8 1,3-dibromo-propane 

Downstream Products

• 327183-32-4 8-formyl-3,4-dihydro-2H-1-benzopyran 
• 1037205-45-0 C₂₅H₂₂FN₃O₅S 
• 1037206-64-6 C₂₆H₂₄FN₃O₅S 
• 1037206-59-9 C₂₆H₂₃FN₂O₄ 
• 1037206-62-4 C₂₅H₂₁FN₂O₄ 
• 3722-78-9 8-bromo-3,4-dihydro-2H-1-benzopyran 

Relevant academic research and scientific papers

4, 5-RING ANNULATED INDOLE DERIVATIVES FOR TREATING OR PREVENTING OF HCV AND RELATED VIRAL INFECTIONS

The present invention relates to 4, 5 - ring annulated indole derivatives of formula ( I ), compositions comprising at leas t one 4, 5 - ring annulated indole derivatives, and methods of using the 4, 5 - ring annulated ^ndole derivatives for treating or preventing a viral inf ection or a virus - related disorder in a patient, (I) wherein ring Z of formula (I), is cyclohexyl, cyclohexenyl, 6-membered heterocycloalkyl, 6- membered heterocycloalkenyl, 6-membered aryl or 6-membered heteroaryl, wherein R1, R2, R3, R6. R7 and R10 are as described herein.

Synthesis of arylpiperazines via palladium-catalysed aromatic amination reactions of bromoarenes with N-tert-butoxycarbonylpiperazine

Reaction of a series of bicyclic bromoarenes with N-tert- butoxycarbonylpiperazine (N-Boc-piperazine) under palladium-catalysed coupling conditions followed by routine removal of the Boc group with trifluoroacetic acid in dichloromethane gave the corresponding arylpiperazines in moderate to good yield.