20640-24-8

Upstream product

• 1439-43-6 1-(4-nitro-phenyl)-2-(triphenyl-λ⁵-phosphanylidene)-ethanone 
• 4974-57-6 4-nitrophenylglyoxal 

Downstream Products

• 1413935-17-7 diethyl 2-(1,2-di(p-nitrobenzoyl)ethyl)propanedioate 
• 1638684-72-6 (2S,3S)-tert-butyl 2,3-bis(4-nitrobenzoyl)-2'-oxospiro[cyclopropane-1,3'-indoline]-1'-carboxylate 
• 1638684-84-0 C₂₉H₂₄ClN₃O₉ 

Relevant academic research and scientific papers

Asymmetric diastereoselective synthesis of spirocyclopropane derivatives of oxindole

A new asymmetric organocatalytic synthesis of spirocyclopropane oxindoles has been developed. The method is based on the Michael addition of N-Boc-protected 3-chlorooxindole to unsaturated 1,4-dicarbonyl compounds, affording trans-substituted spirocyclopropane oxindole derivatives in high diastereo- and enantioselectivity. Copyright

Organocatalytic asymmetric addition of malonates to unsaturated 1,4-diketones

The organocatalytic Michael addition of malonates to symmetric unsaturated 1,4-diketones catalyzed by thiourea and squaramide derivatives with Cinchona alkaloids afforded the formation of a new C-C bond in high yields (up to 98%) and enantiomeric purities (up to 93%). The absolute configuration of the product was suggested from comparison of the experimental and calculated VCD spectra of the reaction product 3a.

Reaction of N-fluoropyridinium salts with Wittig reagents: A novel and convenient approach to symmetric trans-olefins

N-Fluoropyridinium salts were found to react with Wittig reagents containing electron-withdrawing groups to give olefins in 47-83% yield. The mechanism of this conversion is believed in involve single-electron transfer from Wittig reagent to N-fluoropyridinium cation.