1439-43-6

Basic information

• Product Name: 1-(4-nitrophenyl)-2-(triphenyl-lambda~5~-phosphanylidene)ethanone
• CAS NO: 1439-43-6
• Molecular Formula: C₂₆H₂₀NO₃P
• Molecular Weight: 425.4157
• Mol File: 1439-43-6.mol
• Article Data: 22

Chemical Properties

• Boiling Point: 621.5°C at 760 mmHg
• Flash Point: 329.7°C
• Density: 1.28g/cm³
• Vapor Pressure: 2.28E-15mmHg at 25°C
• Refractive Index: 1.66
• CAS DataBase Reference: 1-(4-nitrophenyl)-2-(triphenyl-lambda~5~-phosphanylidene)ethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-nitrophenyl)-2-(triphenyl-lambda~5~-phosphanylidene)ethanone(1439-43-6)
• EPA Substance Registry System: 1-(4-nitrophenyl)-2-(triphenyl-lambda~5~-phosphanylidene)ethanone(1439-43-6)

Safety Data

• Hazardous Substances Data: 1439-43-6(Hazardous Substances Data)

Usage

General Description

1-(4-nitrophenyl)-2-(triphenyl-lambda~5~-phosphanylidene)ethanone is an organic compound that consists of a nitrophenyl group and a phosphanylidene group attached to an ethanone backbone. It is a yellow crystalline substance that is used in organic synthesis and as a reagent in chemical reactions. 1-(4-nitrophenyl)-2-(triphenyl-lambda~5~-phosphanylidene)ethanone is known for its strong electron-withdrawing properties due to the presence of the nitro group, and it is often used in the production of pharmaceuticals and agrochemicals. Additionally, the phosphanylidene group lends itself to various applications in catalysis and coordination chemistry. Due to its unique structure and reactivity, 1-(4-nitrophenyl)-2-(triphenyl-lambda~5~-phosphanylidene)ethanone is a valuable compound in the field of organic chemistry.

Upstream product

• 100-19-6 (4-nitrophenyl)ethanone 
• 16869-24-2 4-nitrobenzyl bromoacetate 
• 603-35-0 triphenylphosphine 
• 99-81-0 4-Nitrophenacyl bromide 
• 7380-84-9 2-(dimethyl-λ⁴-sulfanylidene)-1-(4-nitrophenyl)ethan-1-one 
• 1031-15-8 methyltriphenylphosphonium chloride 
• 122-04-3 4-nitro-benzoyl chloride 
• 17730-93-7 (4'-nitrophenacyl)triphenylphosphonium bromide 

Downstream Products

• 56680-32-1 1-acetyl-3-[2-(4-nitro-phenyl)-2-oxo-ethylidene]-1,3-dihydro-indol-2-one 
• 791-28-6 Triphenylphosphine oxide 
• 6111-97-3 5-(4-nitrophenyl)-1H-1,2,3-triazole 
• 20432-02-4 (E)-4'-nitrochalcone 
• 1286835-50-4 [Pd{κ²(C,C)-C₆H₄PPh₂C(H)CO(C₆H₄-NO₂-4)}(μ-Cl)]₂ 
• 56680-34-3 (E)-3-(2-(4-nitrophenyl)-2-oxoethylidene)indolin-2-one 
• 55210-74-7 (E)-3-(3,5-Dichloro-2-hydroxy-phenyl)-1-(4-nitro-phenyl)-propenone 
• 20640-24-8 trans-1,4-di(p-nitrophenyl)-2-butene-1,4-dione 
• 603-35-0 triphenylphosphine 
• 86429-41-6 (4-Nitrophenylethinyl)triphenylphosphonium-bromid 
• 139266-52-7 5-(4-Methoxy-phenyl)-2-[2-(4-nitro-phenyl)-2-oxo-eth-(Z)-ylidene]-furan-3-one 
• 149281-73-2 2-p-nitrobenzoylmethylene-5-phenyl-2,3-dihydro-3-furanone 

Relevant articles and documents

Rh(iii)-catalyzed diastereoselective cascade annulation of enone-tethered cyclohexadienonesviaC(sp2)-H bond activation

Herein, we report highly diastereoselective arylative cyclization of enone-tethered cyclohexadienonesviaRh(iii)-catalyzed C-H activation ofN-methoxybenzamides. This reaction proceeds through the formation of a five-membered rhodacycle followed by bis-Michael cascade annulation to access functionalized bicyclic scaffolds with four contiguous stereocenters with a broad substrate scope. These products have excellent functional handles, allowing further synthetic transformation to increase the structural complexity. Furthermore, mechanistic studies of arylative cyclization and a gram-scale experiment are also presented.

Copper-Catalyzed N-O Cleavage of α,β-Unsaturated Ketoxime Acetates toward Structurally Diverse Pyridines

The copper-catalyzed [4 + 2] annulation of α,β-unsaturated ketoxime acetates with 1,3-dicarbonyl compounds for the synthesis of three classes of structurally diverse pyridines has been developed. This method employs 1,3-dicarbonyl compounds as C2 synthons and enables the synthesis of multifunctionalized pyridines with diverse electron-withdrawing groups in moderate to good yields. The mechanistic investigation suggests that the reactions proceed through an ionic pathway.

A Ba/Pd Catalytic System Enables Dehydrative Cross-Coupling and Excellent E-Selective Wittig Reactions

A Ba/Pd cooperative catalysis system was developed to enable the dehydrative cross-coupling of allylic alcohols with P-ylides to occur directly and promote a subsequent Wittig reaction in one pot. A variety of multisubstituted 1,4-dienes were isolated in good to excellent yields with broad P-ylides (stabilized by both ester and ketone carbonyl groups) and aldehyde (aliphatic and aromatic) substrates with excellent E selectivity.