206446-45-9

Basic information

• Product Name: 2-(azetidin-3-yl)pyridine dihydrochloride
• Synonyms: 2-(azetidin-3-yl)pyridine dihydrochloride;2-(AZETIDIN-3-YL)PYRIDINE 2HCL
• CAS NO: 206446-45-9
• Molecular Formula: C8H12Cl2N2
• Molecular Weight: 207
• Mol File: 206446-45-9.mol
• Article Data: 3

Chemical Properties

• Melting Point: 174～175℃
• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 2-(azetidin-3-yl)pyridine dihydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(azetidin-3-yl)pyridine dihydrochloride(206446-45-9)
• EPA Substance Registry System: 2-(azetidin-3-yl)pyridine dihydrochloride(206446-45-9)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 206446-45-9(Hazardous Substances Data)

Usage

Description

2-(azetidin-3-yl)pyridine dihydrochloride is a pyridine derivative chemical compound featuring an azetidine group, existing in the form of a dihydrochloride salt. It is utilized in the pharmaceutical industry due to its potential therapeutic effects and requires careful handling in compliance with safety protocols and regulations.

Uses

Used in Pharmaceutical Industry:
2-(azetidin-3-yl)pyridine dihydrochloride is used as a potential therapeutic agent for the treatment of various medical conditions. Its specific applications are still under investigation, necessitating further research to fully explore and understand its capabilities and efficacy in treating different health issues.

Upstream product

• 109-04-6 2-bromo-pyridine 
• 206446-39-1 1-tert-butyl 3-(pyridine-2-yl)azetidine-1-carboxylate 

Relevant articles and documents

Synthetic method of antitumor heterocyclic drug intermediate 2-(3-azacyclobutyl) pyridine dihydrochloride

The invention discloses a synthetic method of an antitumor heterocyclic drug intermediate 2-(3-azacyclobutyl) pyridine dihydrochloride. The synthetic method specifically comprises the following step of performing a two-step reaction to obtain a target compound 2-(3-azacyclobutyl) pyridine dihydrochloride by taking 3-iodine-1-t-butyloxycarboryl azetidine and 2-bromopyridine as raw materials. According to the synthetic method disclosed by the invention, the used raw materials are simple, low in cost and easily available, the reaction condition is simple, and the obtained product is high in chemical purity.

Synthesis of C-substituted cyclic amines using azacycloalkyl organozinc reagents

Azetidine and piperidine derived organozinc species have been prepared from the corresponding azacycloalkyl iodides by direct Zn insertion. They have been shown to readily undergo Pd(0) mediated cross-coupling reactions and to transmetallate with CuCN.2LiCl.