20657-40-3Relevant academic research and scientific papers
Potent and selective double-headed thiophene-2-carboximidamide inhibitors of neuronal nitric oxide synthase for the treatment of melanoma
Huang, He,Li, Huiying,Yang, Sun,Chreifi, Georges,Martásek, Pavel,Roman, Linda J.,Meyskens, Frank L.,Poulos, Thomas L.,Silverman, Richard B.
, p. 686 - 700 (2014/03/21)
Selective inhibitors of neuronal nitric oxide synthase (nNOS) are regarded as valuable and powerful agents with therapeutic potential for the treatment of chronic neurodegenerative pathologies and human melanoma. Here, we describe a novel hybrid strategy
Bidirectional photocontrol of peptide conformation with a bridged azobenzene derivative
Samanta, Subhas,Qin, Chuanguang,Lough, Alan J.,Woolley, G. Andrew
, p. 6452 - 6455 (2012/07/27)
It goes both ways: A thiol-reactive cross-linker based on a bridged azobenzene derivative permits photoreversible control of peptide conformation on irradiation with violet (407a nm) and green (500-550a nm) light (see picture) through isomerization of the
Enantioselective ring-opening reaction of meso-epoxides with ArSH catalyzed by a C2-symmetric chiral bipyridyldiol-titanium complex
Chen, Yi-Jing,Chen, Chinpiao
, p. 1313 - 1319 (2008/02/09)
This study describes a C2-symmetric ligand comprising a central bipyridine-pinene-derived core and two functionalized diphenylmethanol subunits. [8′-(Hydroxy-diphenyl-methyl)-10,10,10′,10′-tetramethy l-[5,5′]bi[6-aza-tricyclo[7.1.1.02,7/s
Libraries for Receptor-Assisted Combinatorial Synthesis (RACS). The olefin metathesis reaction
Giger, Thomas,Wigger, Maria,Audétat, Stephan,Benner, Steven A.
, p. 688 - 691 (2007/10/03)
A library of alkenes is generated using the olefin metathesis reaction, and converted to a set of diols suitable for a receptor assisted combinatorial synthesis (RACS) experiment with borate as a linker.
Electron Transfer in Competition with Loss of Nitrogen in Photochemical Reactions of Aryldiazomethane with Diethylamine
Tomioka, Hideo,Tabayashi, Kazuo,Izava, Yasuji
, p. 906 - 907 (2007/10/02)
The photolysis of aryldiazomethanes was studied as a function of aryl substituents and the p-nitro group was found to exert a special effect of product distribution.
Novel Bis as Antitrypanosomal Agents
Turner, William R.,Werbel, Leslie M.
, p. 1728 - 1740 (2007/10/02)
A series of novel 1,1'-(4,1-phenylene)bis was prepared and evaluated for activity against Trypanosoma rhodesiense in mice.The importance of the bis structure and the nature of the spacer between the two phenyl rings for optimal activity have been revealed.The potent parenteral activity of several analogues within this series as well as preliminary indication of oral activity lends encouragement to further development of this structural class.
