2066512-27-2Relevant articles and documents
MONOACYLGLYCEROL LIPASE MODULATORS
-
Page/Page column 86, (2021/08/20)
3.1.0 and 4.1.0 Azabicycle compounds of Formula (I), pharmaceutical compositions containing them, methods of making them, and methods of using them including methods for treating disease states, disorders, and conditions associated with MGL modulation, su
Borocyclopropanation of Styrenes Mediated by UV-light Under Continuous Flow Conditions
Sayes, Morgane,Benoit, Guillaume,Charette, André B.
, p. 13514 - 13518 (2018/09/25)
Herein, we report a user-friendly and metal-free UV-A light mediated borocyclopropanation of styrenes using continuous flow technology. A broad range of styrene derivatives can be cyclopropanated in good yields within 1 h residence time to produce highly
Diastereoselective borocyclopropanation of allylic ethers using a boromethylzinc carbenoid
Benoit, Guillaume,Charette, André B.
supporting information, p. 1364 - 1367 (2017/02/10)
A borocyclopropanation of (E)- and (Z)-allylic ethers and styrene derivatives via the Simmons-Smith reaction using a novel boromethylzinc carbenoid is described. The carbenoid precursor is prepared via a 3-step sequence from inexpensive and commercially available starting materials. This methodology allows for the preparation of 1,2,3-substituted borocyclopropanes in high yields and diastereoselectivities. Several postfunction-alization reactions were also performed to illustrate the versatility of these building blocks.