206755-02-4

Basic information

• Product Name: 2-Cyclopentene-1-carboxylicacid,4-hydroxy-1-methyl-,methylester,(1S,4S)-
• Synonyms: 2-Cyclopentene-1-carboxylicacid,4-hydroxy-1-methyl-,methylester,(1S,4S)-
• CAS NO: 206755-02-4
• Molecular Formula: C8H12O3
• Molecular Weight: 156.18
• Product Categories: CARBOXYLICESTER
• Mol File: 206755-02-4.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-Cyclopentene-1-carboxylicacid,4-hydroxy-1-methyl-,methylester,(1S,4S)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Cyclopentene-1-carboxylicacid,4-hydroxy-1-methyl-,methylester,(1S,4S)-(206755-02-4)
• EPA Substance Registry System: 2-Cyclopentene-1-carboxylicacid,4-hydroxy-1-methyl-,methylester,(1S,4S)-(206755-02-4)

Safety Data

• Hazardous Substances Data: 206755-02-4(Hazardous Substances Data)

Upstream product

• 108-05-4 vinyl acetate 
• 249537-10-8 (1S,4S)-4-Hydroxy-1-methyl-cyclopent-2-enecarboxylic acid methyl ester 
• 249536-82-1 methyl (1S,2S)-2-acetoxy-1-methyl-3-cyclopentenecarboxylate 
• 206760-78-3 methyl (1S,3S)-2,2-[(1'R,2'R)-cycloheptane-1',2'-dioxy]-3-iodo-1-methylcyclopentane-carboxylate 
• 206760-79-4 methyl (1S)-2,2-[(1'R,2'R)-cycloheptane-1',2'-dioxy]-1-methyl-3-cyclopentenecarboxylate 
• 206755-01-3 methyl (1S,2S)-2-hydroxy-1-methyl-3-cyclopentenecarboxylate 
• 206755-00-2 methyl (1S)-1-methyl-2-oxo-3-cyclopentenecarboxylate 
• 139616-47-0 methyl (1S)-2-((1R,2R)-2-hydroxycycloheptan-1-yl)oxy-1-methyl-2-cyclopenten-1-carboxylate 
• 249536-97-8 methyl (1S,4S)-4-acetoxy-1-methyl-2-cyclopentenecarboxylate 

Downstream Products

• 249536-85-4 (1S,4S)-4-(tert-butyldiphenylsilyloxymethyl)-4-methyl-2-cyclopentenol 

Relevant articles and documents

Stereoselective synthesis of 4'-α-alkylcarbovir derivatives based on an asymmetric synthesis or chemoenzymatic procedure

Stereoselective synthesis of 4'-α-alkylcarbovir derivatives 4 was described based on asymmetric synthesis or a chemoenzymatic procedure. The asymmetric alkylation of chiral acetal 7 gave the alkylated enol ethers 9a - c possessing a chiral quaternary carbon. The key carbocyclic intermediates 14a - c were synthesized from 9a - c via eleven-steps. Coupling of 14a - c with 2-amino-6-chloropurine followed by desilylation and subsequent hydrolysis afforded the target compounds 4a - c in moderate yield. The optically active cyclopentene intermediates 5a - c and 6a - c were also prepared by enzymatic resolution of (±)-5a - c and (±)-6a - c, respectively.