20719-68-0

Usage

Uses

Used in Pharmaceutical Industry:
Isopropylamine, 2-(methoxymethyl)is used as a reagent or intermediate for the synthesis of various pharmaceutical compounds. Its unique structure allows it to be incorporated into the development of new drugs, enhancing their efficacy and properties.
Used in Chemical Industry:
In the chemical industry, Isopropylamine, 2-(methoxymethyl)serves as a key intermediate for the production of various organic compounds. Its ability to form stable bonds with other molecules makes it a valuable component in the synthesis of dyes, pesticides, and other industrial chemicals.
Used in Pesticide Production:
Isopropylamine, 2-(methoxymethyl)is used as a building block in the production of pesticides. Its chemical properties enable it to be incorporated into the formulation of effective and targeted pest control agents, contributing to improved agricultural practices and crop protection.
Used in Dye Manufacturing:
Isopropylamine, 2-(methoxymethyl)is utilized in the manufacturing of dyes due to its ability to form stable color compounds. Its presence in dye formulations contributes to the development of vibrant and long-lasting colorants for various applications, including textiles, plastics, and printing inks.

InChI:InChI=1/C5H13NO/c1-5(2,6)4-7-3/h4,6H2,1-3H3

Upstream product

• 2658-24-4 2,2-dimethylaziridine 
• 67-56-1 methanol 
• 124-68-5 2-Amino-2-methyl-1-propanol 
• 74-88-4 methyl iodide 
• 204707-34-6 tert-butyl (1-methoxy-2-methylpropan-2-yl)carbamate 

Downstream Products

• 2951-54-4 Toluol-4-sulfonsaeure-<β-methoxy-tert.-butylamid> 
• 1236150-05-2 N-(1,1-dimethyl-2-methoxyethyl)-3-iodophthalamic acid 
• 1253787-17-5 N₂-[1,1-dimethyl-2-(methoxy)ethyl]-3-iodo-N₁-[3-(trifluoromethyl)phenyl]-1,2-benzenedicarboxamide 
• 1253787-18-6 N₂-[1,1-dimethyl-2-(methoxy)ethyl]-3-iodo-N₁-[4-chloro-3-(trifluoromethyl)phenyl]-1,2-benzenedicarboxamide 
• 1253787-20-0 N₂-[1,1-dimethyl-2-(methoxy)ethyl]-3-iodo-N₁-[4-cyano-3-(trifluoromethyl)phenyl]-1,2-benzenedicarboxamide 
• 1415149-77-7 C₂₁H₂₃F₃N₂O₅S 
• 1415149-75-5 C₂₁H₂₃F₃N₂O₄S 
• 1415149-79-9 C₂₁H₂₂F₄N₂O₄S 
• 1443156-94-2 C₁₆H₂₅NO₂ 
• 1443157-01-4 C₁₂H₁₇NO₂ 
• 1443156-96-4 C₁₉H₃₃NO₂Si 

Relevant academic research and scientific papers

TRIAZOLYL DERIVATIVES AS SYK INHIBITORS

Provided are triazole derivatives of Formula I which are potent inhibitors of spleen tyrosine kinase and pharmaceutical composition. The triazole derivatives are useful in the treatment and prevention of diseases mediated by said enzyme, such as asthma, COPD, rheumatoid arthritis, and cancer.

PYRAZOLYL DERIVATIVES AS SYK INHIBITORS

The present invention provides novel pyrazole derivatives of formula I which are potent inhibitors of spleen tyrosine kinase, and are useful in the treatment and prevention of diseases mediated by said enzyme, such as asthma, COPD, rheumatoid arthritis, and cancer.

Mechanism of Helix Induction on a Stereoregular Poly((4-carboxyphenyl)acetylene) with Chiral Amines and Memory of the Macromolecular Helicity Assisted by Interaction with Achiral Amines

Cis-transoidal poly((4-carboxyphenyl)acetylene) (poly-1) is an optically inactive polymer but forms an induced one-handed helical structure upon complexation with optically active amines such as (R)-(1-(1-naphthyl)ethyl) amine ((R)-2) in DMSO. The complexes show a characteristic induced circular dichroism (ICD) in the UV-visible region of the polymer backbone. Moreover, the macromolecular helicity of poly-1 induced by (R)-2 can be "memorized" even after complete replacement of (R)-2 by various achiral amines. We now report fully detailed studies on the mechanism of the helicity induction and memory of the helical chirality of poly-1 by means of UV-visible, CD, and infrared spectroscopies. We have found that a one-handed helix is cooperatively induced on poly-1 upon the ion pair formation of the carboxy groups of poly-1 with optically active amines and that the bulkiness of the chiral amines plays a crucial role for inducing an excess of a single-handed helix. On the other hand, the free ion formation was found to be essential for the macromolecular helicity memory of poly-1 after the replacement of the chiral amine by achiral amines, since the intramolecular electrostatic repulsion between the neighboring carboxylate ions of poly-1 significantly contributes to reduce the atropisomerization process of poly-1. On the basis of the mechanism of helicity induction and the memory of the helical chirality drawn from the present studies, we succeeded in creating an almost perfect memory of the induced macromolecular helicity of poly-1 with (R)-2 by using 2-aminoethanol as an achiral chaperoning molecule to assist in maintaining the memory of helical chirality.