20721-07-7

Basic information

• Product Name: Benzoic acid, 4-(phenylsulfonyl)-, hydrazide
• CAS NO: 20721-07-7
• Molecular Formula: C13H12N2O3S
• Molecular Weight: 276.316
• Mol File: 20721-07-7.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 4-(phenylsulfonyl)-, hydrazide(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 4-(phenylsulfonyl)-, hydrazide(20721-07-7)
• EPA Substance Registry System: Benzoic acid, 4-(phenylsulfonyl)-, hydrazide(20721-07-7)

Safety Data

• Hazardous Substances Data: 20721-07-7(Hazardous Substances Data)

Upstream product

• 38337-00-7 methyl 4-(benzenesulfonyl)benzoate 
• 101094-06-8 ethyl 4-(phenylsulfonyl)benzoate 
• 5361-54-6 4-(phenylsulfonyl)benzoic acid 
• 37991-83-6 4-(phenylsulfonyl)benzoyl chloride 
• 640-57-3 phenyltolylsulfone 
• 98-59-9 p-toluenesulfonyl chloride 
• 71-43-2 benzene 

Downstream Products

• 32118-96-0 C₁₈H₂₁N₃O₃S₂ 
• 406934-67-6 4-amino-5-[4-(phenylsulfonyl)phenyl]-2,4-dihydro-3H-1,2,4-triazole-3-thione 
• 1361970-40-2 N₁-[4-(phenylsulfonyl)benzoyl]-N₄-(4-trifluoromethoxyphenyl)-thiosemicarbazide 
• 1361970-44-6 N₁-[4-(phenylsulfonyl)benzoyl]-N₄-(3,4,5-trimethoxyphenyl)-thiosemicarbazide 
• 1361970-47-9 5-(4-(phenylsulfonyl)phenyl)-4-(4-trifluoromethoxyphenyl)-2H-1,2,4-triazol-3(4H)-thione 
• 1361970-49-1 5-(4-(phenylsulfonyl)phenyl)-4-(3,4,5-trimethoxyphenyl)-2H-1,2,4-triazol-3(4H)-thione 
• 1361970-51-5 5-(4-(phenylsulfonyl)phenyl)-N-(4-trifluoromethoxyphenyl)-1,3,4-thiadiazol-2-amine 
• 1361970-53-7 5-(4-(phenylsulfonyl)phenyl)-N-(3,4,5-trimethoxyphenyl)-1,3,4-thiadiazol-2-amine 
• 5454-36-4 N-(4-benzenesulfonyl-phenyl)-N'-butyl-urea 
• 55204-60-9 4-benzenesulfonyl-benzoic acid amide 
• 21849-33-2 (4-benzenesulfonyl-phenyl)-carbamic acid ethyl ester 
• 7019-01-4 p-aminophenyl phenyl sulfone 
• 185428-66-4 N'-(4-Benzenesulfonyl-benzoyl)-hydrazinecarbodithioic acid benzyl ester 
• 185428-56-2 N'-(4-Benzenesulfonyl-benzoyl)-hydrazinecarbodithioic acid methyl ester 

Relevant articles and documents

Design, synthesis, characterization and antimicrobial evaluation of some heterocyclic condensed systems with bridgehead nitrogen from thiazolotriazole class

In the present study, a series of new heterocyclic condensed systems with bridgehead nitrogen from the thiazolo[3,2-b][1,2,4]triazoles class was synthesized starting from some 4-(4-X-phenylsulfonyl)phenyl)-4H-1,2,4-triazole-3-thioles 1a-c (X=H, Cl, Br). The intermediates of S-alkylated 1,2,4-triazoles, 2-(5-(4-(4-X-phenylsulfonyl)phenyl)-2H-1,2,4-triazol-3-ylthio)-1-(4-fluorophenyl)ethanones 2a-c, were obtained by treatment of triazoles 1a-c with 2-bromo-4'-fluoroacetophenone. The 2-(4-(4-X-phenylsulfonyl)phenyl)-6-(4-fluorophenyl)thiazolo[3,2-b][1,2,4]triazoles 3a-c were obtained by cyclization of S-alkylated 1,2,4-triazoles 2a-c in sulfuric acid media, at 0°C. For the synthesis of 2-(4-(4-X-phenylsulfonyl)phenyl)-5-(4-fluorobenzylidene)-thiazolo[3,2-b][1,2,4]triazol-6(5H)-ones 4a-c, the triazoles 1a-c were treated with 4-fluorobenzaldehyde, chloroacetic acid and anhydrous sodium acetate, in the presence of acetic acid and acetic anhydride. The structures of the newly synthesized compounds have been confirmed by elemental analysis and spectral methods (IR, 1H-NMR,13C-NMR, MS). The antimicrobial activity of all new compounds has been screened against some bacteria and yeasts.

Copper(II) and uranyl(II) complexes with acylthiosemicarbazide: Synthesis, characterization, antibacterial activity and effects on the growth of promyelocytic leukemia cells HL-60

New chelates of N1-[4-(4-X-phenylsulfonyl)benzoyl]-N4-butyl-thiosemicarbazide (X = H, Cl, Br) with Cu2+ and UO22+ have been prepared and characterized by analytical and physico-chemical techniques such as magnetic susceptibility measurements, elemental and thermal analyses, electronic, ESR and IR spectral studies. Room temperature ESR spectra of Cu(II) complexes yield {g} values characteristic of distorted octahedral and pseudo-tetrahedral geometry. Infrared spectra indicate that complexes contain six-coordinate uranium atom with the ligand atoms arranged in an equatorial plane around the linear uranyl group. Effects of these complexes on the growth of human promyelocytic leukemia cells HL-60 and their antibacterial activity (against Staphylococcus epidermidis ATCC 14990, Bacillus subtilis ATCC 6633, Bacillus cereus ATCC 14579, Pseudomonas aeruginosa ATCC 9027 and Escherichia coli ATCC 11775 strains) were studied comparatively with that of free ligands.

Studies on 1,3,4-oxadiazoles. Part-X. Preparation and antimicrobial activity of 2-aryl-5-p-phenylsulphophenyl-1-3,4-oxadiazoles

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