640-57-3Relevant articles and documents
Dispersible porous classical polymer photocatalysts for visible light-mediated production of pharmaceutically relevant compounds in multiple solvents
Ferguson, Calum T. J.,Huber, Niklas,Kuckhoff, Thomas,Zhang, Kai A. I.,Landfester, Katharina
, p. 1072 - 1076 (2020)
The dispersibility of photocatalytic polymeric materials is currently a limiting factor for wide scale use. Indeed, the dispersibility of photocatalytic material in solvents dictates its use as heterogenous catalysts, due in part to reagent solubility. Here, we describe a new platform for producing porous polymer photocatalytic nanoparticles that are easily dispersible in a broad range of solvents. Photocatalytic porous classical polymer nanoparticles have been designed, based on classical porous nanoparticles copolymerised with photocatalytic moieties. The combination of both classical and photocatalytic monomers results in an affordable highly photocatalytically effective material, that can be easily dispersed in a wide range of solvents. The versatility and useability of this new material has been demonstrated by photocatalysing a number of pharmaceutically relevant compounds in solvents with varying polarity.
Metal-free sulfonylation of arenes with: N -fluorobenzenesulfonimide via cleavage of S-N bonds: expeditious synthesis of diarylsulfones
Feng, Yueji,Tuo, Yanyan,Zhang, Xiaohui,Zheng, Qing-Zhong
supporting information, p. 768 - 772 (2022/02/03)
A novel metal-free sulfonylation of arenes with N-fluorobenzenesulfonimide (NFSI) toward the synthesis of diarylsulfones has been developed. The reaction represents a rare example of sulfonylation reaction using NFSI as an efficient sulfonyl donor and the first example of acid-mediated sulfonylation of unactivated arenes with NFSI via selective cleavage of S-N bonds. This protocol provides a concise approach for the construction of pharmaceutically and biologically important diarylsulfones. Applications in the functionalization of natural products (e.g., β-estradiol) and in the synthesis of a key intermediate to an inhibitor of farnesyl-protein transferase, as well as in the gram-scale synthesis of the EPAC2 antagonist, are demonstrated. This journal is
Interfacing sugar-based surfactant micelles and Cu nanoparticles: A nanoreactor for C-S coupling reactions in water
Ge, Xin,He, Xi,Liu, Xuemin,Qian, Chao,Song, Weili,Yang, Jinguo,Zhou, Shaodong
supporting information, p. 6322 - 6329 (2021/09/10)
A simple and sustainable synergistic catalytic protocol by interfacing nanomicelles and metal nanoparticles (MNPs) is reported for C-S coupling reactions in water. The sugar-based surfactant GluM was synthesized by introducing a PEG chain to stabilize MNPs and self-assembled to form nanomicelles. Cu2O nanoparticles were generated via in situ reduction of copper salt in an aqueous solution of the sugar-based surfactant. The nature of the interaction between nanomicelles and Cu2O nanoparticles was revealed by XPS, XRD, in situ IR, TEM, and 1H NMR. A broad substrate scope with moderate to excellent yields was documented and the recycling of the GluM/Cu aqueous mixture was surprising.
