640-57-3

Usage

Uses

p-Methyldiphenyl Sulfone is a derivative of diphenyl sulfone

Synthesis Reference(s)

The Journal of Organic Chemistry, 32, p. 2931, 1967 DOI: 10.1021/jo01284a075Synthesis, p. 283, 1984

InChI:InChI=1/C13H12O2S/c1-11-7-9-13(10-8-11)16(14,15)12-5-3-2-4-6-12/h2-10H,1H3

Upstream product

• 3699-01-2 4-tolyl phenyl sulfide 
• 640-60-8 toluene-4-sulfonic acid phenyl ester 
• 10506-59-9 dimethyl disulfate 
• 104-15-4 toluene-4-sulfonic acid 
• 71-43-2 benzene 
• 42840-02-8 2-(Toluene-4-sulfonylamino)-benzoyl chloride 
• 60-29-7 diethyl ether 
• 98-09-9 benzenesulfonyl chloride 
• 98-59-9 p-toluenesulfonyl chloride 
• 80-48-8 methyl p-toluene sulfonate 
• 108-88-3 toluene 
• 300406-05-7 4'-{[(4-methylphenyl)sulfonyl]oxy}[1,1'-biphenyl]-4-yl 4-methylbenzenesulfonate 
• 98-11-3 benzenesulfonic acid 
• 536-57-2 p-toluene sulfinic acid 

Downstream Products

• 860699-53-2 2-tosylbenzoic acid 
• 103626-97-7 5-methyl-2,2'-sulfonyl-di-benzoic acid 
• 536-57-2 p-toluene sulfinic acid 
• 5361-54-6 4-(phenylsulfonyl)benzoic acid 
• 7705-63-7 1-(bromomethyl)-4-(phenylsulfonyl)benzene 
• 83859-32-9 4-tolyl phenyl selenide 
• 854637-15-3 2,4-bis-benzenesulfonyl-toluene 
• 101597-95-9 1-benzenesulfonyl-4-diacetoxymethyl-benzene 
• 13333-14-7 4,4'-Di-benzolsulfonyl-stilben 
• 53348-83-7 C₂₈H₂₂O₂S 
• 13350-35-1 p--stilben 
• 53178-81-7 p-Phenylsulfonyl-α-nitrotoluol 
• 53178-93-1 p-Phenylsulfonyl-α,α-dibrom-α-nitro-toluol 
• 13343-52-7 4-[2-(4-Benzenesulfonyl-phenyl)-1,1-diphenyl-ethyl]-2,6-di-tert-butyl-phenol 

Relevant academic research and scientific papers

Dispersible porous classical polymer photocatalysts for visible light-mediated production of pharmaceutically relevant compounds in multiple solvents

The dispersibility of photocatalytic polymeric materials is currently a limiting factor for wide scale use. Indeed, the dispersibility of photocatalytic material in solvents dictates its use as heterogenous catalysts, due in part to reagent solubility. Here, we describe a new platform for producing porous polymer photocatalytic nanoparticles that are easily dispersible in a broad range of solvents. Photocatalytic porous classical polymer nanoparticles have been designed, based on classical porous nanoparticles copolymerised with photocatalytic moieties. The combination of both classical and photocatalytic monomers results in an affordable highly photocatalytically effective material, that can be easily dispersed in a wide range of solvents. The versatility and useability of this new material has been demonstrated by photocatalysing a number of pharmaceutically relevant compounds in solvents with varying polarity.

Visible-Light-Mediated Late-Stage Sulfonylation of Boronic Acids via N-S Bond Activation of Sulfonamides

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A novel metal-free sulfonylation of arenes with N-fluorobenzenesulfonimide (NFSI) toward the synthesis of diarylsulfones has been developed. The reaction represents a rare example of sulfonylation reaction using NFSI as an efficient sulfonyl donor and the first example of acid-mediated sulfonylation of unactivated arenes with NFSI via selective cleavage of S-N bonds. This protocol provides a concise approach for the construction of pharmaceutically and biologically important diarylsulfones. Applications in the functionalization of natural products (e.g., β-estradiol) and in the synthesis of a key intermediate to an inhibitor of farnesyl-protein transferase, as well as in the gram-scale synthesis of the EPAC2 antagonist, are demonstrated. This journal is

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A Copper(I)-Catalyzed Sulfonylative Hiyama Cross-Coupling

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