20722-53-6Relevant academic research and scientific papers
A Manganese Pre-Catalyst: Mild Reduction of Amides, Ketones, Aldehydes, and Esters
Kelly, Colin M.,McDonald, Robert,Sydora, Orson L.,Stradiotto, Mark,Turculet, Laura
supporting information, p. 15901 - 15904 (2017/12/13)
A new (N-phosphinoamidinate)manganese complex is shown to be a useful pre-catalyst for the hydrosilative reduction of carbonyl compounds, and in most cases at room temperature. The Mn-catalyzed reduction of tertiary amides to tertiary amines, with a useful scope, is demonstrated for the first time by use of this catalyst, and is competitive with the most effective transition-metal catalysts known for such transformations. Ketones, aldehydes, and esters were also successfully reduced under mild conditions by using this new Mn catalyst.
A Convenient Synthetic Route to Methylated Silacyclohexanes
Nguyen, Binh T.,Cartledge, Frank K.
, p. 2206 - 2210 (2007/10/02)
The von Braun degradation of substituted piperidines is a general and economical route to a variety of substituted primary and secondary α,ω-dibromopentanes.Grignard ring closure procedures have been carried out with seven different dibromopentanes in moderate to good yields.Ring closures with MeClSiCl2 lead to product mixtures which are appreciably enriched in one isomer, affording a convenient entry into a variety of derivatives which can be used for stereochemical studies.Assignment of structures based on 1H NMR and mass spectral fragmentation patterns is discussed
