207235-12-9

Upstream product

• 207235-88-9 2-[5-benzyloxycarbonylamino-2-(4-fluorophenyl)-6-oxo-1,6-dihydro-1-pyrimidinyl]-N-[1-[(5-methoxybenzoxazol-2-yl)hydroxymethyl]-2-phenylethyl]acetamide 
• 207235-76-5 2-benzyloxycarbonylamino-1-hydroxy-1-(5-methoxybenzoxazol-2-yl)-3-phenylpropane 
• 207235-75-4 2-amino-1-hydroxy-1-(5-methoxybenzoxazol-2-yl)-3-phenylpropane 
• 66413-45-4 3-(benzyloxycarbonyl)amino-2-hydroxy-4-phenylbutanenitrile 
• 20734-76-3 2-amino-4-methoxyphenol 
• 59830-60-3 N-benzyloxycarbonyl-2-amino-3-phenylpropionaldehyde 

Downstream Products

• 207235-13-0 2-[5-amino-2-(4-fluoro-phenyl)-6-oxo-6H-pyrimidin-1-yl]-N-[1-benzyl-2-(5-methoxy-benzooxazol-2-yl)-2-oxo-ethyl]-acetamide 

Relevant academic research and scientific papers

Synthesis, structure - Activity relationships, and pharmacokinetic profiles of nonpeptidic α-keto heterocycles as novel inhibitors of human chymase

We designed nonpeptidic chymase inhibitors based on the structure of a peptidic compound (1) and demonstrated that the combination of a pyrimidinone skeleton as a P3-P2 scaffold and heterocycles as P1 carbonyl-activating g