20744-02-9

Basic information

• Product Name: 1-methoxy-4-(propan-2-yloxy)benzene
• Synonyms: Benzene, 1-methoxy-4-(1-methylethoxy)-
• CAS NO: 20744-02-9
• Molecular Formula: C₁₀H₁₄O₂
• Molecular Weight: 166.217
• Mol File: 20744-02-9.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 233.6°C at 760 mmHg
• Flash Point: 83.8°C
• Density: 0.973g/cm³
• Vapor Pressure: 0.0845mmHg at 25°C
• Refractive Index: 1.483
• CAS DataBase Reference: 1-methoxy-4-(propan-2-yloxy)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-methoxy-4-(propan-2-yloxy)benzene(20744-02-9)
• EPA Substance Registry System: 1-methoxy-4-(propan-2-yloxy)benzene(20744-02-9)

Safety Data

• Hazardous Substances Data: 20744-02-9(Hazardous Substances Data)

Upstream product

• 75-30-9 2-iodo-propane 
• 150-76-5 4-methoxy-phenol 
• 104-92-7 1-bromo-4-methoxy-benzene 
• 67-63-0 isopropyl alcohol 
• 696-62-8 para-iodoanisole 
• 150-78-7 1,4-dimethoxybezene 

Downstream Products

• 1568-70-3 4-methoxy-2-nitrophenol 
• 15174-02-4 4-hydroxy-2-nitroanisole 
• 56403-51-1 Dicyano-[4-(dicyano-methoxycarbonyl-methyl)-2-isopropoxy-5-methoxy-phenyl]-acetic acid methyl ester 
• 29075-37-4 2-Methoxy-5-isopropyloxy-7,7,8,8-tetracyanochinodimethan 
• 56403-34-0 1,4-Bis(cyanomethyl)-2-methoxy-5-isopropyloxybenzol 
• 86636-11-5 3,5-Dinitro-benzoic acid 4-isopropoxy-phenyl ester 
• 151598-63-9 2-(2-Isopropoxy-5-methoxyanilino)-3-nitropyridine 
• 151598-70-8 4-(2-Isopropoxy-5-methoxyanilino)-3-nitropyridine 
• 151598-72-0 1-(2-Isopropoxy-5-methoxyphenyl)-1H-1,2,3-triazolo<4,5-c>pyridine 
• 151598-65-1 3-(2-Isopropoxy-5-methoxyphenyl)-3H-1,2,3-triazolo<4,5-b>pyridine 
• 151598-71-9 3-Amino-4-(2-isopropoxy-5-methoxyanilino)pyridine 
• 151598-64-0 3-Amino-2-(2-isopropoxy-5-methoxyanilino)pyridine 
• 151598-61-7 2-Isopropoxy-5-methoxyaniline 
• 16169-43-0 4-Isopropoxy-3-nitroanisole 

Relevant articles and documents

MCM-41-immobilized 1,10-phenanthroline-copper(i) complex: A highly efficient and recyclable catalyst for the coupling of aryl iodides with aliphatic alcohols

A heterogeneous C-O coupling reaction between aryl iodides and aliphatic alcohols was achieved in neat alcohol or toluene at 110 °C in the presence of 10 mol% of the MCM-41-immobilized 1,10-phenanthroline-copper(i) complex [MCM-41-1,10-phen-CuI] with Cs2CO3 as a base, yielding a variety of aryl alkyl ethers in good to excellent yields. The new heterogeneous copper catalyst can easily be prepared by a simple procedure from commercially available and inexpensive reagents, and recovered by filtration of the reaction solution and recycled at least 8 times without significant loss of activity.

Bis(μ-iodo)bis[(-)-sparteine]-dicopper: A versatile catalyst for direct O-Arylation and O-Alkylation of phenols and aliphatic alcohols with haloarenes

The easy to prepare dimeric bis(μ-iodo)bis[(-)-sparteine]- dicopper ([CuI{(-)-spa}]2 complex) is shown to be versatile catalyst for O-arylation and O-alkylation with various aryl halides with phenols and aliphatic alcohols respectively, including less reactive aryl chlorides, such as chlorobenzene under mild conditions.

Copper-catalyzed formation of carbon-heteroatom and carbon-carbon bonds

The present invention relates to copper-catalyzed carbon-heteroatom and carbon-carbon bond-forming methods. In certain embodiments, the present invention relates to copper-catalyzed methods of forming a carbon-nitrogen bond between the nitrogen atom of an amide or amine moiety and the activated carbon of an aryl, heteroaryl, or vinyl halide or sulfonate. In additional embodiments, the present invention relates to copper-catalyzed methods of forming a carbon-nitrogen bond between a nitrogen atom of an acyl hydrazine and the activated carbon of an aryl, heteroaryl, or vinyl halide or sulfonate. In other embodiments, the present invention relates to copper-catalyzed methods of forming a carbon-nitrogen bond between the nitrogen atom of a nitrogen-containing heteroaromatic, e.g., indole, pyrazole, and indazole, and the activated carbon of an aryl, heteroaryl, or vinyl halide or sulfonate. In certain embodiments, the present invention relates to copper-catalyzed methods of forming a carbon-oxygen bond between the oxygen atom of an alcohol and the activated carbon of an aryl, heteroaryl, or vinyl halide or sulfonate. The present invention also relates to copper-catalyzed methods of forming a carbon-carbon bond between a reactant comprising a nucleophilic carbon atom, e.g., an enolate or malonate anion, and the activated carbon of an aryl, heteroaryl, or vinyl halide or sulfonate. Importantly, all the methods of the present invention are relatively inexpensive to practice due to the low cost of the copper comprised by the catalysts.