20744-03-0

Basic information

• Product Name: 3-Chloropropyl 4-Methoxyphenyl Ether
• Synonyms: 3-Chloropropyl 4-Methoxyphenyl Ether
• CAS NO: 20744-03-0
• Molecular Formula: C₁₀H₁₃ClO₂
• Molecular Weight: 200.66202
• Product Categories: Aromatics, Pharmaceuticals, Intermediates & Fine Chemicals
• Mol File: 20744-03-0.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• Storage Temp.: -20°C Freezer
• Solubility: Dichloromethane, Dimethylsulfoxide, Ethyl Acetate, Methanol, Hexanes
• CAS DataBase Reference: 3-Chloropropyl 4-Methoxyphenyl Ether(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Chloropropyl 4-Methoxyphenyl Ether(20744-03-0)
• EPA Substance Registry System: 3-Chloropropyl 4-Methoxyphenyl Ether(20744-03-0)

Safety Data

• Hazardous Substances Data: 20744-03-0(Hazardous Substances Data)

Usage

Chemical Properties

Brown Oil

Uses

3-Chloropropyl 4-methoxyphenyl Ether is a reactant used in the preparation of antimycotic imidazoles, antipsychotic agents and piperidines with antihistaminic activity.

Upstream product

• 632-02-0 3-chloropropyl p-toluenesulfonate 
• 150-76-5 4-methoxy-phenol 
• 627-30-5 1-chloro-3-hydroxypropane 
• 109-70-6 1.3-chlorobromopropane 

Downstream Products

• 111626-11-0 4-[bis(4-fluorophenyl)methyl]-1-[3-(4-methoxyphenoxy)propyl]piperidine 
• 5614-78-8 3,4-dihydrobenzopyran-6-ol 
• 150-76-5 4-methoxy-phenol 
• 1417997-98-8 C₂₂H₂₆O₆ 
• 64009-64-9 2-(2,4-Dichlorphenyl)-5-(4-anisyloxy)-pentanol 
• 276690-16-5 (2R,3S,4S,5S)-(-)-1-Benzyloxy-8-(4'-methoxyphenoxy)-3,5-dimethyloctan-2,4-diol 
• 276690-15-4 (2R,3R,5S)-(-)-1-Benzyloxyhydroxy-8-(4'-methoxyphenoxy)-3,5-dimethyloctan-4-one 
• 276690-14-3 (S)-(+)-7-(4'-Methoxyphenoxy)-4-methylheptan-3-one 
• 118943-23-0 1-(3-Iodopropoxy)-4-methoxybenzene 
• 117023-57-1 α,α-Bis(4-fluorophenyl)-1-[3-(4-methoxyphenoxy)propyl]-4-piperidine-methanol 
• 1364171-37-8 1-(4-chlorobenzyl)-4-(3-(4-methoxyphenoxy)propyl)piperazine 
• 1364171-39-0 1-(2-chlorobenzyl)-4-(3-(4-methoxyphenoxy)propyl)piperazine 
• 119917-41-8 2-[(N-(3-(4-methoxy-phenoxy)-propyl)-piperidin-3-yl)methyl]-6,7-dimethyl-1-oxo-1,2,3, 4-tetrahydro-isoquinolinehydrochloride 
• 25836-87-7 N-<3-(4-Methoxy-phenoxy)-propyl>-anilin 

Relevant articles and documents

An efficient multigram-scale synthesis of 4-(ω-chloroalkoxy)phenols

Efficient multigram two-step syntheses of 4-(2-chloroethoxy)phenol and 4-(3-chloropropoxy)phenol in >70% yields starting from 4-hydroxybenzaldehyde and reagents with general formula Cl(CH2)nX (X = Cl, n = 2; X = OTs, n = 3) are proposed. 4-(2-Chloroethoxy)phenol can also be conveniently prepared from 4-methoxyphenol and 1,2-dichloroethane. The compounds thus obtained can be used in carbohydrate chemistry to synthesize glycosides bearing "universal" 4-(ω-chloroalkoxy)phenyl aglycons.

Synthesis and Biological Evaluation of ortho-Aryl N-Hydroxycinnamides as Potent Histone Deacetylase (HDAC) 8 Isoform-Selective Inhibitors

Histone deacetylases (HDACs) are a family of enzymes that play a crucial role in biological process and diseases. In contrast to other isozymes, HDAC8 is uniquely incapable of histone acetylation. In order to delineate its physiological function, we devel

Arylalkylheterocyclic amines,N-substituted by aryloxyalkyl group in a method for allergy treatment

A method of inhibiting Type 1 allergic responses in a living animal body with substituted heterocyclic amines is disclosed wherein the active agents are expressed generally by the formula which includes certain known and certain known compounds: STR1 wherein P is zero, one or two; m is one to six inclusive; A is selected from hydrogen, hydroxy or cyano; d is zero or one; Q is --CH--, CH2 -- or STR2 n is zero or one and when Q is --CH-- and n is one, a double bond is formed with one of the adjacent carbons but not both at the same time, and when n and d are zero at the same time, a double bond is formed between the α carbon and a carbon of the central heterocyclic amine ring; Ar, D and R are selected from phenyl, substituted phenyl, pyridinyl, thienyl, furanyl or naphthyl and in addition, R may have the values benzyl, substituted benzyl, cycloalkyl or loweralkyl and D may additionally have the values: 2H-1-benzopyran-2-one,4-oxo-4H-1-benzopyran-2-carboxylic acid loweralkyl ester, 2,3-dihydro-4H-1-benzopyran-4-one, 1,4-benzodioxanloweralkyl-2-yl or 1,1'-biphenyl-4-yl and the pharmaceutically acceptable salts thereof.