2080-80-0

Upstream product

• 615-79-2 ethyl 2,4-diketopentanoate 
• 539-44-6 N-4-methylphenylhydrazine 

Downstream Products

• 959574-45-9 C₁₂H₁₁ClN₂O 
• 1351169-50-0 3-methyl-N-(1H-tetrazol-5-yl)-1-p-tolyl-1H-pyrazole-5-carboxamide 
• 885-46-1 1-(4-methylphenyl)-3-methyl-1H-pyrazole-5-carboxylic acid 
• 1448994-19-1 2-(2-(5-fluorouracil-1-yl)acetamido)ethyl 1-(4-methylphenyl)-3-methyl-1H-pyrazole-5-carboxylate 

Relevant academic research and scientific papers

Microwave-assisted synthesis of tetrazolyl pyrazole amides

A rapid and efficient microwave-assisted synthesis N-(1H-tetrazol-5-yl) derivatives of 3-methyl-1-phenyl-1H-pyrazole- 5-carboxamide is described. These tetrazole pyrazole amides have interesting bacteriocidal, pesticidal, herbicidal and antimicrobial activities. They were identified by IR and 1H NMR elemental analyses. The target compounds were obtained in a shorter reaction time compared to conventional heating methods.

Functionalized 4-aminoquinolines by rearrangement of pyrazole N-heterocyclic carbenes

(Figure Presented) Thermal decarboxylation of 1-phenyl pyrazolium-3- carboxylates from the mesomeric betaine class of substances leads to pyrazole-N-heterocyclic carbenes, which immediately rearrange to multiply substituted 4-aminoquinolines (see scheme). These species are of interest for the synthesis of heterocycles and pharmacologically active compounds.