20822-61-1

Basic information

• Product Name: triethyl 2-cyanopropane-1,2,3-tricarboxylate
• CAS NO: 20822-61-1
• Molecular Formula: C₁₃H₁₉NO₆
• Molecular Weight: 285.2931
• Mol File: 20822-61-1.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 401°C at 760 mmHg
• Flash Point: 175.4°C
• Density: 1.155g/cm³
• Vapor Pressure: 1.22E-06mmHg at 25°C
• Refractive Index: 1.458
• CAS DataBase Reference: triethyl 2-cyanopropane-1,2,3-tricarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: triethyl 2-cyanopropane-1,2,3-tricarboxylate(20822-61-1)
• EPA Substance Registry System: triethyl 2-cyanopropane-1,2,3-tricarboxylate(20822-61-1)

Safety Data

• Hazardous Substances Data: 20822-61-1(Hazardous Substances Data)

Upstream product

• 773837-37-9 sodium cyanide 
• 105-39-5 chloroacetic acid ethyl ester 
• 105-36-2 ethyl bromoacetate 
• 105-56-6 ethyl 2-cyanoacetate 

Downstream Products

• 99735-28-1 2-ethyl-7-(phenylmethyl)-2,7-diazaspiro<4.4>nonane 
• 99735-27-0 2-methyl-7-(phenylmethyl)-2,7-diazaspiro<4.4>nonane 
• 91189-29-6 2-ethyl-7-(phenylmethyl)-2,7-diazaspiro[4.4]nonane-1,3,8-trione 
• 91189-25-2 2-Methyl-7-(phenylmethyl)-2,7-diazaspiro[4.4]-nonane-1,3,8-trione 
• 91189-24-1 2-methyl-2,7-diazaspiro<4.4>nonane-1,3,8-trione 
• 91189-27-4 (+/-)-3-Carboxy-5-oxo-3-pyrrolidineacetic acid 

Relevant articles and documents

SYNTHESIS OF CYANOCARBOXYLIC ACID ALKYL ESTERS

Provided is a process for obtaining a compound of formula (I): N≡C-CH2-A-C(O)-OR, wherein Hal is halogen selected from F, Cl, Br or I, A denotes a bond or a divalent spacer selected from alkylene and arylene groups, and R is a C1-4 alkyl group, by reacting a compound of formula (II): Hal-CH2-A-C(O)-OR, wherein Hal is a halogen atom selected from F, Cl, Br and I, and wherein A and R are as defined above, with hydrogen cyanide in the presence of a first base, wherein the molar ratio between hydrogen cyanide and said first base is from 1:0.3 to 1:0.95 and the molar ratio between hydrogen cyanide to the compound of formula (II) is at least 1:1.