208335-95-9

Basic information

• Product Name: 1,1-dimethylethyl (4-methylphenyl)sulfonyl(4-pentenyl)carbamate
• Synonyms: 1,1-dimethylethyl (4-methylphenyl)sulfonyl(4-pentenyl)carbamate
• CAS NO: 208335-95-9
• Molecular Weight: 339.456
• Mol File: 208335-95-9.mol
• Article Data: 15

Chemical Properties

• CAS DataBase Reference: 1,1-dimethylethyl (4-methylphenyl)sulfonyl(4-pentenyl)carbamate(CAS DataBase Reference)
• NIST Chemistry Reference: 1,1-dimethylethyl (4-methylphenyl)sulfonyl(4-pentenyl)carbamate(208335-95-9)
• EPA Substance Registry System: 1,1-dimethylethyl (4-methylphenyl)sulfonyl(4-pentenyl)carbamate(208335-95-9)

Safety Data

• Hazardous Substances Data: 208335-95-9(Hazardous Substances Data)

Upstream product

• 18303-04-3 N-[(tert-butoxy)carbonyl]-4-methylbenzenesulfonamide 
• 1119-51-3 bromopentene 
• 70-55-3 toluene-4-sulfonamide 
• 24424-99-5 di-tert-butyl dicarbonate 
• 821-09-0 n-Pent-4-enyl alcohol 

Downstream Products

• 1414335-89-9 C₁₆H₂₃NO₅S 
• 1239683-68-1 (E)-5-(N-(tert-butoxycarbonyl)-4-methylphenylsulfonamido)pent-2-en-1-yl acetate 
• 1602830-85-2 N-(4-chlorobut-2-yn-1-yl)-N-(pent-4-en-1-yl)p-toluenesulfonamide 
• 1602829-55-9 N-(4-chlorobut-2-yn-1-yl)-N-(4-oxopentyl)p-toluenesulfonamide 
• 1602829-87-7 4-methyl-1-tosyl-3-vinylideneazepan-4-ol 
• 81097-24-7 N-tosyl-(4-pentenyl)amine 
• 6435-79-6 2-methyl-1-[(4-methylphenyl)sulfonyl]-pyrrolidine 
• 1609653-27-1 N-tosyl-2-(2,2,2-trifluoroethyl)pyrrolidine 
• 883236-68-8 N-p-toluenesulfonyl-2-(2-phenylethyl)-3-pyrroline 

Relevant articles and documents

A Radical-Initiated Fragmentary Rearrangement Cascade of Ene-Ynamides to [1,2]-Annulated Indoles via Site-Selective Cyclization

Straightforward access to [1,2]-annulated indoles, key substructures in natural products, is highly desirable yet challenging. Herein, a radical triggered fragmentary cyclization cascade reaction of ene-ynamides is presented, providing a rapid access into [1,2]-annulated indoles by an intermolecular radical addition, intramolecular cyclization, desulfonylative aryl migration, and site-selective C(sp2)-N cyclization sequence. DFT calculations support oxidation of N-centered radical species to cations prior to the C-N bond formation, followed by an unusual aza-Nazarov cyclization.

Synthetic efforts toward the Lycopodium alkaloids inspires a hydrogen iodide mediated method for the hydroamination and hydroetherification of olefins

Progress toward the total syntheses of a diverse set of fawcettimine-type Lycopodium alkaloids via a "Heathcock-type" 6-5-9 tricycle is disclosed. This route features an intermolecular Diels-Alder cycloaddition to rapidly furnish the 6-5-fused bicycle and a highly chemoselective directed hydrogenation to build the azonane fragment. While conducting these synthetic studies, trimethylsilyl iodide was found to effect a hydroamination reaction to furnish the tetracyclic core of serratine and related natural products. This observation has been expanded into a general method for the room temperature hydroamination of unactivated olefins with tosylamides utilizing catalytic "anhydrous" HI (generated in situ from trimethylsilyl iodide and water). The presence of the iodide anion is critical to the success of this Bronsted acid catalyzed protocol, possibly due to its function as a weakly coordinating anion. These conditions also effect the analogous hydroetherification reaction of alcohols with unactivated olefins.

Efficient copper-catalyzed direct intramolecular aminotrifluoromethylation of unactivated alkenes with diverse nitrogen-based nucleophiles

A mild, convenient, and step-economical intramolecular aminotrifluoromethylation of unactivated alkenes with a variety of electronically distinct, nitrogen-based nucleophiles in the presence of a simple copper salt catalyst, in the absence of extra ligand