20834-59-7

Basic information

• Product Name: FEMA 3242
• Synonyms: 8-HYDROXY-P-CYMENE;PARA METHYL DIMETHYL BENZYL CARBINOL;P,ALPHA,ALPHA-TRIMETHYLBENZYL ALCOHOL;P-CYMEN-8-OL;.alpha.,.alpha.,4-trimethyl-Benzeneethanol;alpha,alpha,4-trimethyl-benzeneethano;alpha,alpha,4-trimethylphenethyl alcohol;P-Methyl benzyl dimethyl carbinol
• CAS NO: 20834-59-7
• Molecular Formula: C₁₁H₁₆O
• Molecular Weight: 164.25
• EINECS: 214-817-7
• Mol File: 20834-59-7.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 64 °C0.6 mm Hg(lit.)
• Flash Point: 205 °F
• Appearance: /
• Density: 0.97 g/mL at 25 °C(lit.)
• Refractive Index: n20/D 1.5185(lit.)
• CAS DataBase Reference: FEMA 3242(CAS DataBase Reference)
• NIST Chemistry Reference: FEMA 3242(20834-59-7)
• EPA Substance Registry System: FEMA 3242(20834-59-7)

Safety Data

• WGK Germany: 2
• Hazardous Substances Data: 20834-59-7(Hazardous Substances Data)

Usage

General Description

FEMA 3242, also known as cis-3-Hexen-1-ol, is a natural organic compound found in fruits and vegetables with a fresh, leafy green aroma. It is widely used as a flavoring agent in the food and beverage industry, adding a natural and refreshing green note to various products. Additionally, FEMA 3242 is utilized in the fragrance industry for its green, grassy scent, and it can also be found in cosmetics and personal care products. This chemical is generally recognized as safe (GRAS) by the Food and Drug Administration (FDA) and is considered non-toxic in normal usage concentrations.

Upstream product

• 2096-86-8 p-Tolylaceton 
• 917-54-4 methyllithium 
• 106-42-3 para-xylene 
• 35675-44-6 4-methylphenylacetyl chloride 
• 89980-67-6 p-methylbenzylmagnesium bromide 
• 67-64-1 acetone 
• 917-64-6 methyl magnesium iodide 
• 23786-13-2 methyl p-tolylacetate 
• 104-82-5 4-Methylbenzyl chloride 
• 622-47-9 4-tolylacetic acid 
• 23304-24-7 p-tolyldiazomethane 
• 67-63-0 isopropyl alcohol 
• 109-92-2 ethyl vinyl ether 
• 14062-19-2 p-tolylacetic acid ethyl ester 

Downstream Products

• 19956-97-9 2,2,6-trimethyl-2,3-dihydro-benzofuran 
• 1373042-04-6 C₁₇H₂₈N₂O 
• 1357290-74-4 KMI-1895 
• 1373041-98-5 C₂₀H₃₂N₂O 
• 1267527-84-3 2-chloro-N-(2-methyl-1-(p-tolyl)propan-2-yl)acetamide 
• 1379575-57-1 t-butyl 2-(2-methyl-1-p-tolylpropan-2-yl)hydrazinecarboxylate 
• 67510-95-6 2-methyl-1-(p-tolyl)propan-2-amine 
• 1379577-36-2 4-(4-hexylphenyl)-1-(2-methyl-1-(p-tolyl)propan-2-yl)-1H-pyrazol-5-ol 
• 34586-20-4 1-p-Methylbenzyl-1-methylethyl-p-nitroperbenzoat 

Relevant articles and documents

Tripeptidic BACE1 inhibitors devised by in-silico conformational structure-based design

Previously reported pentapeptidic BACE1 inhibitors, designed using a substrate-based approach, were used as lead compounds for the further design of non-peptidic BACE1 inhibitors. Although these peptidic and non-peptidic inhibitors, with a hydroxymethylcarbonyl isostere as a substrate transition-state mimic, exhibited potent BACE1 inhibitory activities, their molecular-sizes appeared a little too big (molecular weight of >600 daltons) for developing practical anti-Alzheimer's disease drugs. To develop lower weight BACE1 inhibitors, a series of tripeptidic BACE1 inhibitors were devised using a design approach based on the conformation of a virtual inhibitor bound to the BACE1 active site, also called 'in-silico conformational structure-based design'. Although these tripeptidic BACE1 inhibitors contained some natural amino acid residues, they are expected to be useful as lead compounds for developing the next generation BACE1 inhibitors, due to their low molecular size and unique structural features compared with previously reported inhibitors.

Fragrance compositions containing 2-cyclohexyl-1,1-dimethyl ethanol esters

A fragrance, having a 2-cyclohexyl-1,1-dimethyl ethanol derivative represented by formula (1), wherein R represents a hydrogen atom or an acetyl group, Me represents a methyl group and n represents an integer from 0 to 3, provides a very pleasing scent, has excellent stability in a product, and can be mixed well with other fragrances.

PHOTOCHEMICAL OXIDATION AND DIMERIZATION OF ALKYLBENZENES. SELECTIVE REACTIONS OF THE ALKYL SIDE GROUPS

Irradiations of alkylbenzene compounds in an oxygen atmosphere result exclusively in oxidation reactions, while in a less oxidative environment dimerization processes predominate.Under all conditions studied, the reactions took place only at one benzyl position.