208665-77-4

Upstream product

• 100-39-0 benzyl bromide 
• 22273-77-4 ((but-3-yn-1-yloxy)methyl)benzene 
• 89121-83-5 (2R/S)-6-(benzyloxy)hex-3-yn-2-ol 
• 917-54-4 methyllithium 

Downstream Products

• 847552-67-4 (2R,3E)-6-(benzyloxy)-2-{[(N,N-diisopropyl)carbamoyl]oxy}hex-3-ene 
• 847552-65-2 (2R,3E)-6-(benzyloxy)hex-3-en-2-ol 
• 847552-68-5 (2S,3E)-6-(benzyloxy)-2-{[(N,N-diisopropyl)carbamoyl]oxy}hex-3-ene 
• 847552-63-0 (2R/S,3E)-6-(benzyloxy)-2-{[(N,N-diisopropyl)carbamoyl]oxy}hex-3-ene 
• 208665-83-2 (E)-6-Benzyloxy-2-bromomethyldimethylsilyloxyhex-3-ene 

Relevant academic research and scientific papers

Secondary allyltitanium(IV) reagents in aldehyde allylation I: Extension of the Hoppe reaction to γ-alkoxy secondary allyl carbamates

An efficient access to optically active (R)- or (S)-γ-alkoxy allyltitanium(IV) intermediates, in aldehyde allylation reactions, is described. Enantiomeric γ-alkoxy secondary allyl carbamates (R)- and (S)-14 were first prepared. Determination of their enan

Sequential radical cyclization of β-functionalized allyl bromomethyldimethylsilyl ethers. Application to the regioand stereo-specific synthesis of an isoprostanoid precursor

The behaviour of allyl bromomethyldimethylsilyl ethers β-substituted by various radical trapping functions (aldehyde, nitrile or acetylenic) is studied in tandem radical cyclizations. Only homopropargylic ethers (but-3ynylic ethers) lead to the formation of cyclic compounds via a 5-exo-trig, 5-exo-dig or 5-exo-trig, 6-endo-dig mode. The influence of the TMS group located on the acetylenic moiety is shown to be determinant for the regio- and stereo-specific C5 ring closure (5-exo-clig mode).

New acyclic β-functionnalized (E) allyl alcohols and their bromomethyldimethylsilyl ethers as cyclopentanoids precursors

The syntheses of new acyclic (E) allyl alcohols β-functionnalized by various radical trapping functions and their corresponding bromomethyldimethylsilyl ethers are reported.