208665-95-6

Usage

Uses

Used in Organic Synthesis:
3-bromo-4-(2-methylpropoxy)benzonitrile serves as a valuable building block in the realm of organic synthesis. Its unique structure makes it a key component in the preparation of a diverse array of pharmaceuticals, agrochemicals, and other fine chemicals. Its versatility in chemical reactions and compatibility with various synthetic pathways contribute to its widespread application in the development of new and improved chemical products.
Used in Pharmaceutical Industry:
Within the pharmaceutical sector, 3-bromo-4-(2-methylpropoxy)benzonitrile is utilized as a crucial intermediate in the synthesis of various medicinal compounds. Its presence in the molecular structure of these compounds can influence their pharmacological properties, such as potency, selectivity, and bioavailability. 3-bromo-4-(2-methylpropoxy)benzonitrile's reactivity and functional groups enable the creation of new drug candidates with potential therapeutic benefits.
Used in Agrochemical Industry:
In the agrochemical industry, 3-bromo-4-(2-methylpropoxy)benzonitrile is employed as a precursor in the synthesis of pesticides and other crop protection agents. Its incorporation into these chemical products can enhance their effectiveness in controlling pests and diseases, thereby contributing to increased crop yields and improved agricultural productivity.

InChI:InChI=1/C11H12BrNO/c1-8(2)7-14-11-4-3-9(6-13)5-10(11)12/h3-5,8H,7H2,1-2H3

Upstream product

• 2973-78-6 3-bromo-4-hydroxybenzylaldehyde 
• 767-00-0 4-cyanophenol 
• 78-77-3 Isobutyl bromide 
• 2315-86-8 3-bromo-4-hydroxybenzonitrile 

Downstream Products

• 208665-96-7 3-bromo-4-isobutoxyphenylthiocarboxamide 
• 161718-81-6 4-isobutoxyisophthalonitrile 
• 1350352-72-5 2-[3-cyano-4-(2-methylpropoxy)phenyl]-4-methylthiazole-5-carboxylic acid tert-butylamine 
• 1350352-71-4 2-[3-cyano-4-(2-methylpropoxy)phenyl]-4-methylthiazole-5-carboxylic acid methylamine 
• 163597-57-7 3-cyanoisobutoxybenzothioamide 
• 160844-75-7 2-(3-cyano-4-isobutyloxyphenyl)-4-methylthiazole-5-carboxylic acid ethyl ester 
• 144060-53-7 febuxostat 

Relevant academic research and scientific papers

HCl·DMPU-assisted one-pot and metal-free conversion of aldehydes to nitriles

We report an efficient HCl·DMPU assisted one-pot conversion of aldehydes into nitriles. The use of HCl·DMPU as both an acidic source as well as a non-nucleophilic base constitutes an environmentally mild alternative for the preparation of nitriles. Our protocol proceeds smoothly without the use of toxic reagents and metal catalysts. Diverse functionalized aromatic, aliphatic and allylic aldehydes incorporating various functional groups were successfully converted to nitriles in excellent to quantitative yields. This protocol is characterized by a broad substrate scope, mild reaction conditions, and high scalability. This journal is

2 - (3-cyano-4-alkoxy) phenyl-4-substituted thiazole-5- formic acid class compound, composition and its preparation and use

The invention relates to a 2-(3-cyano-4-alkoxy) phenyl-4-substituted thiazole-5-formic acid compound which has xanthine oxidase inhibitory activity and is shown in a general formula I, a composition and preparation methods thereof. The invention also relates to applications of the compound and the composition thereof to preparation of medicaments for treating and/or preventing hyperuricemia and gout diseases. In the formula I, R2 is substituted or unsubstituted phenyl or a substituted or unsubstituted heteroaromatic radical, R1 is a substitutive aliphatic group of a straight chain or a branched chain, substituted or unsubstituted alicyclic hydrocarbonyl or substituted or unsubstituted aryl alkyl and A is an oxygen atom, a sulfur atom or a nitrogen atom.

PROCESS FOR THE PREPARATION OF 2-[3-CYANO-4-(2-METHYLPROPOXY)PHENYL]-4-METHYLTHIAZOLE-5-CARBOXYLIC ACID AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS

The present invention relates to novel and improved processes for the preparation of 2-[3-cyano-4-(2-methylpropoxy) phenyl]-4-methylthiazole-5-carboxylic acid compound of formula-1 and its pharmaceutically acceptable salts thereof. the present invention also provides the novel process for the preparation of crystalline forms of 2-[3-cyano-4-(2-methylpropoxy) phenyl]-4-methylthiazole-5-carboxylic acid compound of formula-1 and its intermediates.

A PROCESS FOR THE PREPARATION OF FEBUXOSTAT

The present invention relates to a process for the preparation of Febuxostat, useful in the pharmaceutical field for the treatment of the hyperuricemia.