20873-58-9 Usage
Chemical Properties
Off-white solid
Uses
5-(Methylthio)thiophene-2-carboxylic Acid is used to prepare acylated piperidinylmethyl and azabicyclomethyl pyridinemethanamines as selective 5-HT1a superagonists for potential use in the treatment of CNS disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 20873-58-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,0,8,7 and 3 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 20873-58:
(7*2)+(6*0)+(5*8)+(4*7)+(3*3)+(2*5)+(1*8)=109
109 % 10 = 9
So 20873-58-9 is a valid CAS Registry Number.
InChI:InChI=1/C6H6O2S2/c1-9-5-3-2-4(10-5)6(7)8/h2-3H,1H3,(H,7,8)
20873-58-9Relevant articles and documents
Halogen-magnesium exchange on unprotected aromatic and heteroaromatic carboxylic acids
Kopp, Felix,Wunderlich, Stefan,Knochel, Paul
, p. 2075 - 2077 (2008/02/09)
The magnesiation of halogenated aromatic and heteroaromatic carboxylic acids is accomplished by their treatment with MeMgCl in the presence of LiCl and subsequent reaction with i-PrMgCl·LiCl; the resulting double-magnesiated species react with a variety of electrophiles in up to 97% yield. The Royal Society of Chemistry.
