5780-36-9

Usage

Uses

Used in Synthetic Chemistry:
2-(METHYLTHIO)THIOPHENE is used as an intermediate in synthetic chemistry for the production of various organic compounds. Its reactivity and structural properties make it a valuable building block in the synthesis of complex molecules.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2-(METHYLTHIO)THIOPHENE is used as a key component in the synthesis of certain pharmaceutical compounds. Its unique chemical properties allow for the development of new drugs with potential therapeutic applications.
Used in Chemical Research:
2-(METHYLTHIO)THIOPHENE is also utilized in chemical research for studying the properties and reactions of sulfur-containing compounds. Its use in research contributes to the advancement of knowledge in organic chemistry and the development of new synthetic methods.
Used in the Preparation of 2-Thiocyanato-Thiophene:
2-(METHYLTHIO)THIOPHENE is used in the preparation of 2-thiocyanato-thiophene, a compound with potential applications in various fields. The reaction involves the use of cyanogen iodide and sodium methylmercaptide as reagents, showcasing the versatility of 2-(METHYLTHIO)THIOPHENE in chemical synthesis.

InChI:InChI=1/C5H6S2/c1-6-5-3-2-4-7-5/h2-4H,1H3

Upstream product

• 1003-09-4 2-bromothiophene 
• 4670-62-6 tetra-N-butylammonium benzenethiolate 
• 74-88-4 methyl iodide 
• 188290-36-0 thiophene 
• 624-92-0 Dimethyldisulphide 

Downstream Products

• 24445-35-0 5-(methylthio)thiophene-2-carboxaldehyde 
• 38695-60-2 Methyl-<2>thienylsulfon 
• 20873-58-9 5-(methylthio)thiophene-2-carboxylic acid 
• 74166-42-0 (+/-)-2-(methylsulfinyl)thiophene 
• 82187-66-4 ethyl 2-(thiophen-2-sulfanyl)acetate 
• 50878-66-5 2,5-bis(methylsulfanyl)thiophene 
• 100-68-5 methyl-phenyl-thioether 
• 884488-45-3 2-bromo-1-[5-(methylthio)thiophen-2-yl]ethanone O-benzyloxime 
• 1172999-13-1 4,4,5,5-tetramethyl-2-[5-(methylthio)thiophen-2-yl]-1,3,2-dioxaborolane 
• 1610373-74-4 3-(5-(methylsulfinyl)thiophen-2-yl)benzaldehyde 
• 1610372-77-4 5,7-dimethoxy-2-(3-(5-(methylsulfinyl)thiophen-2-yl)phenyl)quinazolin-4(3H)-one 
• 2160-61-4 2-bromo-5-(methylsulfonyl)thiophene 
• 86369-96-2 2-bromo-5-(methylthio)thiophene 
• 103647-60-5 5-methylsulfanyl-thiophene-2-carbaldehyde-(4-nitro-phenylhydrazone) 

Relevant academic research and scientific papers

Catalytic reactions of dimethyl disulfide with thiophene and benzene

The gas-phase reaction of dimethyl disulfide with thiophene proceeds under the action of acid catalysts under atmospheric pressure at 160-350°C and a residence time of τ = 0.6-21 s to form thioalkylation and alkylation products. Dimethyl disulfide reacts with benzene to form only alkylation products. Catalysts containing both strong protic and Lewis acid sites, as well as basic sites of moderate strength, are the most active ones.

Reaction of dimethyl disulfide with thiophene catalyzed by zeolite

Reaction of dimethyl disulfide with thiophene under the action of highly siliceous zeolite at 180-350°C and contact time 0.6-14 s resulted in formation of thioalkylation products, 2-(methylsulfanyl)- and 2,5-bis(methylsulfanyl)thiophenes and also alkylate

Photostimulated SRN1 Reactions of Halothiophenes with Benzenethiolate Ion in Acetonitrile

The photostimulated reactions between benzenethiolate and 2-chloro-, 2-bromo-, 2-iodo-, and 3-bromothiophene in MeCN lead to rather complex product mixtures where the phenyl thienyl sulfide(ThSPh), the ipso-substitution product, represents the main component.The collected results agree well with the occurrence of an SRN1 chain pathway.As to the obtainable yield of sulfide, the main drawback is represented by the fragmentation into ThS- and Ph(radical) of the ThSPh radical anion, formeded either along the propagation cycle or by single-electron reduction of the sulfide itself.Optimization of the yield of ThSPh, although at the expense of the overall reaction rate, can be achieved by the employment of suitable electron acceptors.The overall reactivity orders (2-I > 2-Br > 2-Cl and 2-Br > 3-Br) are also discussed.