20886-47-9

Upstream product

• 139-02-6 sodium phenoxide 
• 108-88-3 toluene 
• 3350-78-5 3,3-Dimethylacryloyl chloride 
• 100-61-8 N-methylaniline 
• 34876-10-3 3-methyl-2-butenoic anhydride 
• 121-69-7 N,N-dimethyl-aniline 
• 541-47-9 3-Methylbutenoic acid 

Downstream Products

• 10229-37-5 N-(3-methylbut-2-enyl)-N-methylaniline 
• 58461-27-1 (+/-)-lavandulol 
• 20886-50-4 N,3-Dimethyl-2,3-epoxybutananilide 
• 104643-26-7 N,N-diisopropyl-10-methyl-8-oxoundeca-1,5,9-triene-6-carboxamide 
• 104663-58-3 2-(3'-butenyl)-N,N-diisopropyl-N'-phenyl-N',4,4-trimethyl-1,3-cyclopentanedicarboxamide 
• 104643-16-5 2-(3'-butenyl)-N,N-diisopropyl-N'-phenyl-N',3,3-trimethyl-1,4-cyclopentanedicarboxamide 
• 104643-06-3 2-Eth-(E)-ylidene-4,4-dimethyl-hexanedioic acid 1-diisopropylamide 6-(methyl-phenyl-amide) 
• 104643-05-2 (1R,3S,5S)-4,4,5-Trimethyl-cyclopentane-1,3-dicarboxylic acid 1-diisopropylamide 3-(methyl-phenyl-amide) 
• 67986-78-1 N,5-dimethyl-N-phenyl-2-isopropenyl-4-hexenamide 

Relevant academic research and scientific papers

Synthesis of hydroxyl-containing oxindoles and 3,4-dihydroquinolin-2-ones through oxone-mediated cascade arylhydroxylation of activated alkenes

Hydroxyl-containing compounds are highly value-Added organic molecules, and the establishment of novel methodologies for their elaboration is a long-standing challenge in organic synthesis. Here the first oxone-mediated direct arylhydroxylation of activat

Amide bond formation through iron-catalyzed oxidative amidation of tertiary amines with anhydrides

A general and efficient method for amide bond synthesis has been developed. The method allows for synthesis of tertiary amides from readily available tertiary amines and anhydrides in the presence of FeCl2 as catalyst and tert-butyl hydroperoxide in water (T-Hydro) as oxidant. Mechanistic studies indicated that the in situ-generated α-amino peroxide of tertiary amine and iminium ion act as key intermediates in this oxidative transformation.

On the preparation of amine N-oxides by using dioxiranes

The reaction of heterocyclic aromatic amines, anilines and tertiary amines with dimethyldioxirane (DMD) was examined. Treatment of heterocyclic aromatic amines and anilines with a slight excess of DMD at 0°C afforded the corresponding N-oxides in quantitative conversion yields. In addition, the oxidation was chemoselective in the presence of carbon-carbon double bonds. On the other hand, most of the tertiary amines assayed did afford also quantitative yields of the corresponding N. oxides, although reaction conditions, in particular regarding the amount of DMD required, depended on each substrate. Additional studies carried out on selected substrates suggested that certain N-oxides derived from tertiary amines deactivate DMD.