2089-31-8

Usage

Uses

Used in Pharmaceutical Industry:
Ethanone, 1-[4-(1-methylethyl)phenyl]-, oxime is used as a pharmaceutical intermediate for the synthesis of various drugs. Its unique structure and oxime functional group make it a valuable building block in the development of new pharmaceutical compounds.
Used in Agricultural Industry:
In the agricultural industry, Ethanone, 1-[4-(1-methylethyl)phenyl]-, oxime may be used as a precursor for the synthesis of agrochemicals, such as pesticides and herbicides. Its reactivity and ability to form various chemical compounds make it a useful component in the development of effective agricultural products.
Used in Research:
Ethanone, 1-[4-(1-methylethyl)phenyl]-, oxime is used as a research compound in various scientific studies. Its unique properties and reactivity make it an interesting subject for exploration in the fields of organic chemistry, coordination chemistry, and other related disciplines.
Used as a Ligand in Coordination Chemistry:
Ethanone, 1-[4-(1-methylethyl)phenyl]-, oxime can be used as a ligand in coordination chemistry. Its oxime functional group can form coordination bonds with metal ions, making it a useful component in the synthesis of metal complexes with potential applications in catalysis, sensing, and other areas.
Used as a Reagent in Organic Synthesis:
Due to its reactivity and ability to participate in various chemical reactions, Ethanone, 1-[4-(1-methylethyl)phenyl]-, oxime can be used as a reagent in organic synthesis. It can be employed in the synthesis of a wide range of organic compounds, including pharmaceuticals, agrochemicals, and other specialty chemicals.

Upstream product

• 98-82-8 Isopropylbenzene 
• 645-13-6 4-isopropylacetophenone 

Downstream Products

• 88054-93-7 1-Vinyl-2-(p-isopropenylphenyl)pyrrole 
• 134899-65-3 N-{1-[(E)-4-Isopropyl-phenylimino]-ethyl}-3-nitro-N-(4-nitro-phenyl)-benzenesulfonamide 
• 645-13-6 4-isopropylacetophenone 
• 93971-52-9 2-(4-isopropylphenyl)-1H-pyrrole 
• 5702-74-9 N-(4-iso-propylphenyl)acetamide 

Relevant academic research and scientific papers

Rhodium-Catalyzed C?H Activation/Annulation Cascade of Aryl Oximes and Propargyl Alcohols to Isoquinoline N-Oxides

A β-hydroxy elimination instead of common oxidization to carbonyl group in secondary propargyl alcohols was successfully developed to form 2-benzyl substituted isoquinoline N-oxides by a Rhodium-catalyzed C?H activation and annulation cascade, in which moderate to excellent yields (up to 92%) could be obtained under mild reaction conditions, along with good regioselectivity, broad generality and applicability. (Figure presented.).

Rhodium(iii)-catalyzed asymmetric [4+1] spiroannulations of: O -pivaloyl oximes with α-diazo compounds

Chiral RhIII catalysts can catalyze the asymmetric [4+1] spiroannulation of O-pivaloyl oximes with α-diazo homophthalimides under redox-neutral and acid/base-neutral conditions, leading to formation of chiral spirocyclic imines as a result of C-H activation and N-O cleavage. The reaction proceeded with high efficiency and features broad substrate scope, mild reaction conditions, and high to excellent enantioselectivities. This journal is

SO2F2-Activated Efficient Beckmann Rearrangement of Ketoximes for Accessing Amides and Lactams

A novel, mild and practical protocol for the efficient activation of the Beckmann rearrangement utilizing the readily available and economical sulfuryl fluoride (SO2F2 gas) has been developed. The substrate scope of the operationally simple methodology has been demonstrated by 37 examples with good to nearly quantitative isolated yields (over 90 % yield in most cases) in a short time, including B(OH)2, COOH, NH2, and OH substituted substrates. A tentative mechanism was proposed involving formation and elimination of key intermediate, sulfonyl ester.

Redox-Neutral Access to Isoquinolinones via Rhodium(III)-Catalyzed Annulations of O-Pivaloyl Oximes with Ketenes

A mild and redox-neutral [4 + 2] annulation of O-pivaloyl oximes with ketenes has been realized for synthesis of quaternary-carbon-stereocenter-containing (QCSC) isoquinolinones, where the N-OPiv not only acts as an oxidizing group but also offers coordination saturation to inhibit protonolysis. The reaction mechanism has been studied by DFT calculations.

Rh(III)- and Zn(II)-Catalyzed Synthesis of Quinazoline N-Oxides via C-H Amidation-Cyclization of Oximes

Quinazoline N-oxides have been prepared from simple ketoximes and 1,4,2-dioxazol-5-ones via Rh(III)-catalyzed C-H activation-amidation of the ketoximes and subsequent Zn(II)-catalyzed cyclization. The substrate scope and functional group compatibility were examined. The reaction features relay catalysis by Rh(III) and Zn(II).