208924-93-0Relevant academic research and scientific papers
Mild N-dealkylation of tertiary, benzylic amines with acid chlorides: Application to solid-phase chemistry
Miller, Michael W.,Vice, Susan F.,McCombie, Stuart W.
, p. 3429 - 3432 (1998)
A mild, facile cleavage of appropriately substituted tertiary benzylic amines with acid chlorides is described for both solution and solid phase.
Microwave-assisted solvent-free parallel synthesis of thioamides
Olsson,Hansen,Andersson
, p. 7947 - 7950 (2007/10/03)
Rapid parallel synthesis of thioamides is described. A library of amides, synthesised by mixing acyl chlorides and diamines, was transformed into the corresponding thioamides utilising Lawesson's reagent as the oxygen/sulphur exchange reagent. Purification by solid-phase extraction afforded the library members in adequate purities and yields. (C) 2000 Elsevier Science Ltd.
